摘要
目的对孕兔行肺通气/灌注显像检查,观察孕兔所产子代情况,从而为肺通气/灌注显像检查的临床应用提供一定的理论依据。方法将符合实验要求的孕兔随机分为对照组和检查组,检查组孕兔孕8d时行肺通气灌注显像检查。孕期观察两组孕兔子代在流产、死胎等方面有无差异,在孕晚期检测母体血甲状腺激素水平,了解子代宫内发育情况。产时、产后观察两组孕兔子代死产、外观畸形情况,产后1d和75d观察测量两组孕兔子代生长发育方面是否存在差异。结果两组孕兔子代在流产、死胎、死产方面差异无统计学意义(P>0.05);孕晚期母体血甲状腺激素水平,两组差异无统计学意义(P>0.05)。两组孕兔子代外观均未见明显畸形,所产子代在产后1d和75d体质量、头围、腹围及身长等指标差异均无统计学意义(P>0.05)。结论肺通气/灌注显像检查对孕兔子代在流产、死胎、死产、外观致畸以及子代生长发育方面未发现明显不良影响。
Objective To examine the pregnancy outcomes of rabbits being subjected to pulmonary ventilation perfusion imaging examinations. Methods Pregnant rabbits were randomly divided into two groups： control group and experimental （lung ventilation-perfusion scintigraphy） group. The pregnancy outcomes were measured using indicators of miscarriage, premature birth, and stillbirth, as well as malformations and developmental abnormalities of offspring over a three-month period. Results No significant differences in miscarriage, premature birth, and stillbirth were found between the two groups. No obvious deformity appearances in the offspring were observed. The two groups showed no statistically significant differences in fetal progeny-intrauterine growth and developmental indicators measured by body mass, head circumference, abdominal circumference and length. Conclusion Lung ventilation-perfusion scintigraphy examination has no effects on pregnant outcomes measured by miscarriage, premature birth, stillbirth, fetal teratogenicity and fetal growth.
出处
《四川大学学报（医学版）》
CAS
CSCD
北大核心
2016年第6期866-868,共3页
Journal of Sichuan University(Medical Sciences)
关键词
兔
肺通气/灌注显像
胎儿
Rabbits
Lung ventilation-perfusion seintigraphy examination
Fetus
