期刊文献+

评价表柔比星联合紫杉醇在三阴性乳腺癌中的临床应用价值 被引量:1

Evaluation of Clinical Application Value of Combined Paclitaxel and Paclitaxel in Three Negative Breast Cancer
在线阅读 下载PDF
导出
摘要 目的评价表柔比星联合紫杉醇在三阴性乳腺癌的临床应用价值。方法选取在我院治疗的54例局部晚期三阴性乳腺癌患者作为研究对象,对其随机分组。对照组采用表柔比星单药治疗,实验组采用表柔比星联合紫杉醇治疗,比较两组患者的临床疗效及不良反应发生率。结果实验组患者的治疗有效率为62.96%,高于对照组,P<0.05,但两组之间的不良反应发生情况差异无统计学意义,P>0.05。结论表柔比星联合紫杉醇在三阴性乳腺癌治疗中具有较显著的临床疗效。 Objective To analyze the clinical effect of the combination of epirubicin and paclitaxel in the treatment of three negative breastcancer. Methods 54 cases of three negative breast cancer patients treated in our hospital were selected as the target, random grouping of the implementation. The control group was treated with the epirubicin, the experimental group was treated with the combination of the epirubicin and paclitaxel, compared with the two groups of patients with clinical efficacy and adverse reaction rate. Results The effective rate of the experimental group was 62.96%, which was significantly higher than that of the control group, P〈0.05, but there was no significant difference in the incidence of adverse reactions between the two groups, P〈0.05. Conclusion The combination of epirubicin and paclitaxel in the treatment of three negative breast cancer has a significant clinical effect.
作者 胡春霞
出处 《中国继续医学教育》 2016年第30期134-135,共2页 China Continuing Medical Education
关键词 表柔比星 紫杉醇 三阴性乳腺癌 Epirubicin Paclitaxel Three negative breast cancer
  • 相关文献

参考文献9

二级参考文献70

  • 1杨庄青,邹天宁,刘德权,李梅,王茂华,李少林.表柔比星联合紫杉醇治疗三阴性乳腺癌的效果分析[J].中国生化药物杂志,2014,34(6):113-115. 被引量:27
  • 2Voogd AC, Van Tienhoven G, Peterse HL, et al. Local recurrence after breast conservation therapy for early stage breast carcinoma : Group on Local Recurrence after Breast conservation(BORST)[J]. Cancer, 2009,85 : 437-446.
  • 3Wapnir IL, Anderson SJ,Mamounas EP,et al. Prognosis after Ipsilateral breast tumor recurrence and locoregional recurrences in five national surgical adjuvant breast and bowel project node positive ad- juvant breast trial[J]. J Clin Oncol,2007,82t287-293.
  • 4Kreike B, Van Kouwenhove M, Horlings H, et al. Gene expression profiling and histopathological characterization of triple negative basal--like breast careinomas[J].Breast Cancer Ras,2007,9:65.
  • 5Bhattacharyya A,Ear US,Koter BH,et al. The breast cancer susceptibility gene BRCA1 is required for subnuclear assembly of Rad51 and survival following treatment with the DNA cross--linking agent cisplatin[J]. Biol ehem,2009,275(31) :23899.
  • 6孙燕 周际昌.临床肿瘤内科手册[M].北京:人民卫生出版社,1998.45.
  • 7Jemal A, Bray F, Center MM, et al. Global cancer statistics[ J].CA Cancer J Clin, 2011 ;61 : 69 -90.
  • 8Rakha EA, El - Sayed ME, Green AR, et al. Prognostic markers intriple - negative breast cancer[J]. Cancer, 2007; 109:25 -32 .
  • 9Dent R,Trudeau M,Pritchard KI,et al. Triple - negative breastcancer: Clinical features and patterns of recurrence[ J]. Clin CancerRes, 2007;13:4429-4434 .
  • 10Jemal A, Siegel R, Ward E, et al. Cancer statistics,2009[ J]. CACancer J Clin, 2009;59: 225 -249.

共引文献143

同被引文献19

引证文献1

二级引证文献16

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部