摘要
目的探讨荧光支气管镜检查在肺癌早期诊断中的价值。方法将我院432例行支气管镜检查的患者分为观察组和对照组，每组216例，观察组行荧光支气管镜检查，对照组行白光支气管镜检查，观察患者镜下表现及病理检查结果，将两组获取的活检组织和（或）细胞学标本送我院病理科检查。结果观察组镜下鳞癌的检出率[38．0％（82／216）]明显高于对照组[15．7％（347216）]（X2=27．15，P〈0．05）；观察组不典型增生、原位癌、肺癌的检出率明显高于对照组（P〈0．05）；两组镜下表现差异无统计学意义（P〉0．05）。结论荧光支气管镜利用荧光染色确定肺癌的病变部位及范围，与传统的白光气管镜检查相比可显著提高肺癌的检出率，在早期肺癌的诊断中有较高的临床应用价值。
Objective To explore the application value of the fluorescence bronchoscope exami- nation in the diagnosis of lung cancer. Methods 432 patients with bronchoscopy in our hospita were divided into observation group and control group, 216 cases in each group. Fluorescence bronchoscope examination was conducted in observation group, and white light bronchoscopy was conducted in the control group, then to observe characteristics under bronchoscopy. Biopsy samples and （or） cytology specimens of the two groups were sent to our pathology department, and to compare their results. Results The detection rate of the microscopic squamous cell carcinomas of observation group was 38.0% （82/216）, which was significantly higher than that of the control group（ 15.7%, 34/216） and there was statistical significant（ X2 = 27.15, P 〈0. 05 ）. The incidences of atypical hyperplasia, carcinoma in situ and lung cancer of the observe group were significantly higher than those of the control group and there were statistically significance （P 〈 0.05 ） between two groups. There was no significant difference（ P 〉 0.05 ） in performance of two groups under the bronchoscope. Conclusion Fluorescent bronchoscopy examination is a kind of method which use fluorescent dye to determine the lesion site and the range. Compared with traditional white light bronchoscope examination,it can improve the detection rate of lung cancer and has higher application value in the diagnosis of lung cancer.
出处
《临床内科杂志》
CAS
2016年第11期747-749,共3页
Journal of Clinical Internal Medicine
关键词
支气管镜
荧彤白光
肺癌
Bronchoscope, fluorescence/white light
Lung cancer
