摘要
目的探讨腹腔镜抽芯法输卵管切除术对卵巢储备的影响及血清抗苗勒氏管激素（AMH）评价卵巢储备的优越性。方法选取输卵管妊娠住院手术患者共82例，年龄20—40岁，分为3组，A组20例行腹腔镜下抽芯法输卵管切除术，B组30例行腹腔镜下输卵管开窗取胚术，C组32例行腹腔镜下传统法输卵管切除术。比较3组患者术前、术后1月和术后4月血清AMH、促卵泡素（FSH）、黄体生成素（LH）、雌二醇（E2）及抑制素B（INHB）水平。结果3组患者术前血清AMH水平比较差异无统计学意义（P〉0．05）；C组术后4月血清AMH水平（2．15±0.40）ng／ml显著低于术前（1．50±0．40）ng／ml，P〈0．05；A组和B组手术前后各时点血清AMH水平比较差异尤统计学意义（P〉0．05）；3组血清FSH、LH、E2及1NHB水平在手术前后各时点均无统计学差异（P〉0．05）。结论腹腔镜抽芯法输卵管切除术对卵巢储备无明显影响；血清AMH在评价卵巢储备方面优于血清FSH、LH、E2及INHB。
Objective To explore the effect of core-pulling salpingectomy on ovarian reserve tunction and the superiority of serum anti-Mtillerian hormone （AMH） in evaluation of ovarian reserve function. Methods Eighty-two patients aged 20-40 years old with tubal pregnancy were selected and divided into three groups： 20 patients in group A were treated by core-pulling salpingeetomy, 30 patients in group B were treated by laparoscopic salpingostomy, and 32 patients in group C were treated by conventional salpingostomy. The levels of serum AMH, follicle-stimulating hormone （FSH） , luteinizing hormone （LH） , estradiol （E2 ） , and inhibin B （INHB） before operation and after one month and four months of operation in the three groups were compared. Results Thele was no statistically significant difference in serum AMH level before operation among the three groups （P〉0. 05 ） ; the level of AMH after four months of operation in group C was （2. 15±0.40） ng/ml, which was statistically significantly lower than that before operation [ （ 1.50±0. 40） ng/ml] （P〈0.05） ; there was no statistically significant difference in serum AMH level at different time points before and after operation between group A and group B （P〉 0. 05 ） ; there was no statistically significant difference in the levels of serum FSH, LH, E2, and INHB at dilterent time points before and after operation among the three groups （P〉0. 05 ） . Conclusion Core-pulling salpingectomy has no significant impact on ovarian reserve function; serum AMH is superior to serum FSH, LH, E2 , and INHB regarding to evaluating ovarian reserve function.
出处
《中国妇幼保健》
CAS
2016年第23期5112-5114,共3页
Maternal and Child Health Care of China
基金
南京医科大学科技发展基金重点项目(2013NJMU202)
无锡市医院管理中心联合攻关项目(YGZXL1301)
关键词
输卵管切除术
抗苗勒氏管激素
卵巢储备
Salpingectomy
Anti-Mullefian hormone
Ovarian reserve function
