摘要
目的观察丙泊酚复合小剂量右美托咪啶用于无痛人工流产（以下简称人流）麻醉的临床疗效。方法，选取2015年2月至2015年12月拟行无痛人流手术患者100例，将其随机分为观察组和对照组，每组50例。观察组麻醉前先静脉缓慢泵注小剂量右美托咪啶，再给予丙泊酚静脉麻醉；对照组单一应用丙泊酚静脉麻醉。观察两组麻醉效果、丙泊酚用量、清醒时间、术后腹痛、注射痛，以及手术麻醉期间呼吸抑制、心动过缓和低血压的发生情况。结果观察组麻醉效果优于对照组，注射痛发生率低于对照组，两组相比较差异有统计学意义（P〈O．01）。观察组术后腹痛、呼吸抑制发生率低于对照组，两组比较差异有统计学意义（P〈0．05）。两组术后清醒时间及术中发生心动过缓、低血压等比较差异未见统计学意义（P〉0．05）。结论丙泊酚复合小剂量右美托咪啶应用于无痛人流手术麻醉效果确切，术后腹痛、注射痛、呼吸抑制等不良反应少，值得临床推广。
Objective To explore the curative effects of propofol combined with small dose dexme- detomidine used for anesthesia of painless abortion surgery. Methods One hundred patients receiving painless abortion surgery from February 2015 to December 2015 were selected and randomly divided into the observation group and the control group. Fifty cases in each group. Patients in the observation group were firstly intravenous pumping injected with small dose dexmedetomidine before anesthesia, and then propofol was used for intravenous anesthesia. Patients in the control group only used propofol for intravenous anes- thesia. The anesthesia effects, propofol consumption, awake time, epigastric pain, injection pain, as well as respiratory depression, bradycardia, hypotension during the anesthesia were observed between the two groups. Results The anesthetic effect of the patients in observation group was better than that in control group, and the incidence rate of injection pain in the observation group was lower than that in control group, the differences between the two groups were statistically significant （P 〈 0. 01 ）. The incidence rate of epigastric pain and respiratory depression in observation group decreased significantly compared with the control group, the difference between the two groups was statistically significant （ P 〈 O. 05 ）. There was no significant difference of awake time after operation, bradycardia or hypotension during the anesthesia between the two groups （P 〉 0. 05）. Conclusions The anesthetic effects of propofol com- bined with small dose dexmedetomidine used for anesthesia of painless abortion surgery are definite, and the occurrence rates of postoperative adverse reactions such as epigastric pain, injection pain, and respir-atory depression are low. It＇ s worthwhile to further its application.
出处
《中国实用医刊》
2016年第23期54-56,共3页
Chinese Journal of Practical Medicine
关键词
右美托咪啶
丙泊酚
无痛人工流产
Dexmedetomidine
Propofol
Painless abortion surgery
