摘要
目的分析近4年本院4种主要阴性菌耐药率,研究四者之间的相关性。方法采用回顾性统计分析,利用WHONET5.6和SPSS 19.0软件进行统计分析。回顾本院2012—2015年住院患者中分离的4种阴性菌每半年的耐药率,运用双变量相关分析相关性。结果大肠埃希菌、肺炎克雷伯菌与铜绿假单胞菌三种细菌的耐药率逐年下降,鲍曼不动杆菌的耐药率逐年上升。正相关性(r>0)明显(P<0.05)的抗菌药物有头孢哌酮/舒巴坦,氨曲南,环丙沙星。负相关性(r<0)明显(P<0.05)的有哌拉西林、头孢吡肟,阿米卡星。结论本院主要阴性细菌耐药率变化复杂;其变化趋势有待于继续动态监测。
Objective To analyze the drug resistance rates of 4 main negative bacteria in our hospital in recent 4 years, and to study the correlation between the four. Methods Statistical analysis was performed using WHONET 5.6 and SPSS 19 software. To review the drug resistance rate of 4 negative bacteria isolated from inpatients in our hospital during the year of 2012---2015, and to analyze the correlation between the two variables. Results E. coli, Klebsiella pneumoniae and Pseudomonas aeruginosa three bacteria resistant rate decline year by year, while the Acinetobacter baumannii resistant rate increased year by year. The antibacterial drugs including cefoperazone/sulbactam, aztreonam, ciprofloxacin showed a obvious positive correlation （r〉0, P〈0.05）.while piperacillin, cefepime, amikacin showed a obvious negative correlation （r〈0, P〈0.05）. Conclusion Our main negative bacteria resistant complex. Its resistance to be continue to dynamic monitoring.
出处
《国外医药（抗生素分册）》
CAS
2017年第1期14-18,共5页
World Notes on Antibiotics
关键词
大肠埃希菌
鲍曼不动杆菌
耐药率
抗菌药物
相关性
Escherichia coli
Acinetobacter baumannii
drug resistance
antimicrobial agents： correlation
