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阿尔茨海默病与脑衰老

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摘要 衰老是伴随着增龄出现的机体结构退行性变和机能的减退,衰老也是应激、炎性反应、内分泌代谢紊乱所致结果。而在社会学方面,衰老是对新鲜事物兴趣减弱、超脱现实、喜欢怀旧等等。神经系统是重要的机能调节系统,也是受衰老影响最大的系统之一,衰老的脑组织会产生一些特征性的改变,从而导致疾病发生。
作者 李鸿雁 王蓉
出处 《老年医学与保健》 CAS 2016年第6期331-334,共4页 Geriatrics & Health Care
基金 国家自然科学基金(81472007) 首都卫生发展科研专项(首发2014-1-1031)
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  • 1Furth EE, Gustafson KS, Dai CY, Gibson SL, Menard-Katch- er P, Chen T, Koh J, Enders GH. Induction of the tumor- suppressor pl6(INK4a) within regenerative epithelial crypts in ulcerative colitis. Neoplasia 2006; 8:429-436.
  • 2Usselmann B, Newbold M, Morris AG, Nwokolo CU. Defi- ciency of colonic telomerase in ulcerative colitis. Am J Gas- troentero12001; 96:1106-1112.
  • 3Kleideiter E, Friedrich U, Mohring A, Walker S, Horing E, Maier K, Fritz P, Thon KP, Klotz U. Telomerase activity in chronic inflammatory bowel disease. Dig Dis Sci 2003; 48: 2328-2332.
  • 4Sipos F, Galamb O, Herszenyi L, Molnar B, Solymosi N, Zagoni T, Berczi L, Tulassay Z. Elevated insulin-like growthfactor 1 receptor, hepatocyte growth factor receptor and telomerase protein expression in mild ulcerative colitis. Scand J Gastroenterol 2008; 43:289-298.
  • 5Salminen A, Huuskonen J, Ojala J, Kauppinen A, Kaarni- ranta K, Suuronen T. Activation of innate immunity system during aging: NF-kB signaling is the molecular culprit of inflamm-aging. Ageing Res Rev 2008; 7:83-105.
  • 6Desai A, Grolleau-Julius A, Yung R. Leukocyte function in the aging immune system. J Leukoc Biol 2010; 87:1001-1009.
  • 7Bettelli E, Korn T, Kuchroo VK. Th17: the third member of the effector T cell trilogy. Curr Opin Immuno12007; 19:652-657.
  • 8Weaver CT, Harrington LE, Mangan PR, Gavrieli M, Mur- phy KM. Th17: an effector CD4 T cell lineage with regula- tory T cell ties. Immunity 2006; 24:677-688.
  • 9Korn T, Bettelli E, Oul~ka M, Kuchroo VK. IL-17 and Th17 Cells. Annu Rev Immuno12009; 27:485-517.
  • 10Ouyang X, Yang Z, Zhang R, Arnaboldi P, Lu G, Li Q, Wang W, Zhang B, Cui M, Zhang H, Liang-Chen J, Qin L, Zheng F, Huang B, Xiong H. Potentiation of Th17 cytokines in aging process contributes to the development of colitis. Cell Immuno12011; 266:208-217.

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