摘要
目的:探讨槐杞黄颗粒预防儿童过敏性紫癜(Henoch-Sch?nlein purpura,HSP)复发的疗效及其对免疫功能的影响。方法:对照组30例,为临床常规治疗;治疗组30例,在临床常规治疗的基础上,加用槐杞黄颗粒。观察2组HSP患儿在1月、3月内的复发情况,并比较2组患儿治疗后的免疫功能变化。结果:治疗组在治疗1月、3月内的复发率均低于对照组,2组比较差异有统计学意义(P<0.05),治疗前2组HSP患儿外周血CD3、CD4、CD8、CD4/CD8、IgG、IgA、IgM比较,差异均无统计学意义(P>0.05),治疗后治疗组CD3、CD4、CD4/CD8明显高于对照组,且差异有统计学意义(P<0.05),而IgA低于一般治疗组,差异有统计学意义(P<0.05)。结论:槐杞黄颗粒对调节机体免疫功能,降低HSP的复发率有一定的作用。
Objective： To explore the effect of Huaiqihuang granule in preventing he relapse of Henoch-Schonlein purpura（HSP） in children and the effect on immune function. Methods： There were 30 patients in control group whom received conventional treatment. There were 30 patients in treatment group whom received the Huaiqihuang granule besides the same therapy as control group. The relapse rate was recorded with lmonths and 3 months after course of treatment.Compare the changes of immune globulin and T-lymphocyte subsets between two group after course of treat- ment. Results： The relapse rate in treatment group was significantly lower than that of control group （P〈0.05）. The level of CD3, CD4, CDS, CD4/CD8, IgG, IgA and IgM between the two groups before treatment had no significant difference （P〉0.05）. After treatment by Huaiqihuang granule, the level of CD3, CD4 and ratio of CD4/CD8 in treatment group were significantly higher than those in control group （P〈0.05）, meanwhile IgA in treatment group was significantly lower than that in control group （P〈0.05）. Conclusion： Huaiqihuang granule is effective for regulating the body＇ s immune function and reducing the relapse rate.
作者
赵爽
方琪玮
邓祥露
ZHAO Shuang FANG Qiwei DENG Xianglu(Shanxi University of Traditional Chinese Medicine, Shanxi Taiyuan 030024, China Children＇s Hospital of Shanxi, Shanxi Taiyuan 030002, China)
出处
《中医药临床杂志》
2017年第1期122-124,共3页
Clinical Journal of Traditional Chinese Medicine
关键词
槐杞黄颗粒
儿童过敏性紫癜
免疫功能
复发
Huaiqihuang granule
Henoch-Schonlein purpura（HSP） in children
Immune function, Relapse
