摘要
目的观察拉贝洛尔联合硫酸镁对妊娠期高血压疾病的治疗效果。方法将我院收治的90例妊娠期高血压患者按随机数字表法分为观察组和对照组,每组各45例。对照组患者单独给予硫酸镁,观察组在对照组基础上给予拉贝洛尔。治疗1周后,观察比较两组患者治疗前后血压、心率及24 h尿蛋白变化情况,同时比较两组患者不良反应的发生情况。结果治疗后,观察组患者收缩压、舒张压、心率及24 h尿蛋白较对照组下降(P<0.05);且两组患者不良反应率对比,差异不具有统计学意义(P>0.05)。结论拉贝洛尔联合硫酸镁治疗妊娠期高血压疗效显著,能够显著改善患者临床症状,且不增加患者不良反应安全性高。
Objective To observe the effects of labetalol combined with magnesium sulfate in treating hypertensive disorder complicating pregnancy. Methods 90 cases patients with hypertensive disorder complicating pregnancy in our hospital were randomly divided into the observation group and the control group, 45 cases in each group. The control group was treated with magnesium sulfate alone, while the observation group was additionally treated with labetalol. After 1 week of treatment, the changes of blood pressure, heart rate and 24 hours urine protein were observed and the incidence of adverse reactions were compared between the two groups. Results After treatment, the systolic blood pressure, diastolic blood pressure, heart rate and 24 hours urine protein in the observation group were lower than those in the control group（P〈0.05）. and the differences in adverse reactions between the two groups were no significant（P〉0.05）. Conclusion Labetalol combined with magnesium sulfate is effective in the treatment of hypertensive disorder complicating pregnancy, and the effect in relieving the clinical symptoms and reducing the incidence of adverse reactions is significantly better than magnesium sulfate alone.
出处
《中国继续医学教育》
2017年第2期182-183,共2页
China Continuing Medical Education
关键词
拉贝洛尔
硫酸镁
妊娠期高血压
疗效
labetalol
magnesium sulfate
hypertensive disorder complicating pregnancy
curative effect
