摘要
目的探讨左氧氟沙星三联治疗幽门螺杆菌临床治疗效果。方法 100例幽门螺杆菌感染患者,随机分为对照组与观察组,各50例。对照组患者给予常规三联疗法,口服雷贝拉唑+阿莫西林+克拉霉素治疗7 d;观察组患者则以左氧氟沙星三联治疗,口服雷贝拉唑+左氧氟沙星+阿莫西林治疗7 d。分析比较两组患者临床治疗效果、不良反应发生率。结果经7 d治疗后,观察组幽门螺杆菌根除率96.0%高于对照组的60.0%,差异有统计学意义(P<0.05);观察组不良反应发生率6.0%低于对照组的20.0%,差异有统计学意义(P<0.05)。结论以左氧氟沙星三联治疗方式治疗幽门螺杆菌感染患者,临床效果显著、安全稳定,值得临床广泛应用。
Objective To explore clinical effect of levofloxacin trigeminy therapy in radical treatment of helicobacter pylori. Methods A total of 100 patients with helicobacter pylori infection were randomly divided into control group and observation group, with 50 cases in each group. The control group received conventional trimodality therapy, with oral rabeprazole＋amoxicillin＋ clarithromycin for 7 d, and the observation groupreceivedlevofloxacin trigeminy therapy, with oral rabeprazole ＋ levofloxacin ＋ amoxicillin for 7 d. Analysisand comparison on clinical effect andincidence of adverse reactionsin two groups. Results After 7 d treatment, the observation grouphad higherhelicobacter pylori radical rate as 96.0% than 60.0% inthecontrolgroup, and the difference had statistical significance（P〈0.05）; the observation group hadlower incidence of adverse reactionas6.0% than 20.0%in the control group, and the difference had statistical significance（P〈0.05）.Conclusion Levofloxacin trigeminy therapy showssignificant clinical effect, security and stabilityin the treatmentof helicobacter pylori, and worthwildly clinicalapplication.
出处
《中国现代药物应用》
2017年第1期106-107,共2页
Chinese Journal of Modern Drug Application
关键词
左氧氟沙星
三联治疗
幽门螺杆菌
Levofloxacin
Trigeminy therapy
Helicobacter pylori
