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多模式CT指导下静脉溶栓治疗急性脑梗死与预后的相关性 被引量:9

The prognosis correlation of multi mode CT guided intravenous thrombolysis for acute cerebral infarction
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摘要 目的:探讨多模式CT指导下静脉溶栓与动脉溶栓治疗急性脑梗死与预后的相关性。方法:2014-02-2016-04选择在我院诊治的急性脑梗死患者86例,根据多模式CT指导具有溶栓治疗指征,用电脑简单随机化方法把患者分为观察组与对照组各43例,对照组给予动脉溶栓,观察组给予静脉溶栓,观察2组预后情况。结果:溶栓后观察组与对照组的显效率分别为69.8%和46.5%,观察组的显效率明显高于对照组(P<0.05)。观察组与对照组溶栓后NIHSS评分分别为(6.13±2.18)分和(10.44±3.20)分,都明显低于溶栓前的(18.32±3.10)分和(18.83±2.78)分,观察组溶栓后评分也明显低于对照组(P<0.05)。观察组溶栓期间的肠系膜栓塞、消化道出血、脑出血、肺部感染、尿路感染等并发症发生率为7.0%,对照组为32.6%,观察组明显少于对照组(P<0.05)。结论:相对于动脉溶栓,多模式CT指导下静脉溶栓治疗急性脑梗死具有更好的安全性,能提高脑神经,从而促进预后的改善,有很好的应用价值。 Objective:To investigate the prognosis correlation of multi mode CT guided intravenous thrombolysis for acute cerebral infarction.Method:From February 2014 to April 2016,86 cases of acute cerebral infarction patients in our hospital were selected,all the patients were under the guidance of multi-mode CT had thrombolytic therapy indications.Accorded the computer simple randomization methods,the patients were were equally divided into observation group and control group with 43 cases in each group.The control group was treated with intra-arterial thrombolysis,the observation group were given intravenous thrombolytic therapy,the prognosis in the two groups were observed.Result:The significant efficiency of the observation group and the control group were 69.8% and 46.5%respectively,the significant efficiency of the observation group was significantly higher than that of the control group(P〈0.05).The NIHSS scores after thrombolysis in the observation group and control group were(6.13±2.18)points and(10.44±3.20)points respectively that were significantly lower than those before thrombolysis of(18.32±3.10)points and(18.83±2.78)points,and the scores after thrombolysis group in the observation group were significantly lower than that of control group(P〈0.05).The incidence rate of mesenteric embolism,gastrointestinal bleeding,cerebral hemorrhage,pulmonary infection and urinary tract infection in the observation group was 7.0%,while the control group was 32.6%,and the observation group was significantly less than the control group(P〈0.05).Conclusion:Compare with the arterial thrombolysis,the multi mode CT guidance in the treatment of acute cerebral infarction with intravenous thrombolysis has better safety,IT can improve the brain nerve,so as to promote the improvement of prognosis that has good application values.
出处 《临床急诊杂志》 CAS 2017年第1期41-43,47,共4页 Journal of Clinical Emergency
基金 2014年十堰市科学技术研究与开发项目(No:14Y71)
关键词 动脉溶栓 静脉溶栓 多模式CT 预后 并发症 arterial thrombolysis intravenous thrombolysis multi mode CT prognosis complication
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