摘要
目的探讨奥美拉唑联合生长抑素和蛇毒血凝酶治疗急性上消化道出血的临床效果。方法选择2013年3月~2016年3月在我院治疗的急性上消化道出血患者82例,随机分为实验组和对照组,各41例,实验组采用奥美拉唑联合生长抑素和蛇毒血凝酶治疗,对照组仅采用奥美拉唑治疗,比较两组止血效果、止血时间、不良反应发生率及患者和家属满意度。结果实验组止血有效率及患者和家属满意率均显著高于对照组(P<0.05),实验组止血时间显著短于对照组(P<0.05),且不良反应发生率低于对照组,差异有统计学意义(P<0.05)。结论奥美拉唑联合生长抑素和蛇毒血凝酶治疗急性上消化道出血的效果更确切,可快速止血,稳定生命体征,显著缩短止血时间,不良反应少,安全性好,患者和家属满意度良好,值得临床推广。
Objective To explore the effect of Omeprazole combined with somatostatin and snake venom blood clotting enzyme in the treatment of acute upper gastrointestinal bleeding.Methods From March 2013 to March 2016,82 acute upper gastrointestinal bleeding patients were randomly divided into experimental group and control group,41 cases in each groups.The experimental group was adopted Omeprazole combined with somatostatin and snake venom blood clotting enzyme,the control group only was adopted Omeprazole.The hemostatic effect,hemostatic time,the incidence of adverse reactionsand patients′ satisfaction of two groups were compared Results The hemostatic effect and the patients′satisfaction were significantly higher than those of control group（P〈0.05）,the hemostatic time was significantly shorter than the control group（P〈0.05）,the incidence of adverse reactions was lower than that of control group,that of difference was significant（P〈0.05）.Conclusion The experimental group has exact curative effect,shorter hemostatic time and less adverse reactions.The patients are almost satisfied with it,which is worth to promoting.
作者
曾志明
ZENG Zhi-ming(Department of Emergency,People＇s Hospital of Guangning County in Zhaoqing City,Guangdong Province,Guangning 526300,Chin)
出处
《中国当代医药》
2017年第5期134-136,共3页
China Modern Medicine
关键词
生长抑素
蛇毒血凝酶
奥美拉唑
急性上消化道出血
Somatostatin
Snake venom blood clotting enzyme
Omeprazole
Acute upper gastrointestinal bleeding
