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氧驱雾化吸入普米克令舒治疗小儿哮喘急性发作疗效及对肺功能的影响 被引量:58

Clinical effect of oxygen atomization inhalation of pulmicort in treatment of children with acute exacerbation of asthma and the impact on lung function
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摘要 目的探讨氧驱雾化吸入普米克令舒治疗小儿哮喘急性发作的疗效以及对肺功能的影响。方法选取接受治疗的小儿哮喘急性发作患儿84例随机分为观察组和对照组各42例,对照组患儿给予常规治疗,观察组患儿给予氧驱雾化吸入治疗。观察两组患儿治疗后呼吸困难、肺部哮鸣音、喘息、咳嗽消失时间以及住院时间,比较两组患儿治疗前后肺功能改善情况、治疗后的临床效果以及满意度。结果治疗后,观察组患儿呼吸困难、肺部哮鸣音、喘息以及咳嗽消失时间明显少于对照组患儿,住院时间明显少于对照组患儿,两组比较差异均有统计学意义(P<0.05)。治疗前两组患儿FEV1、PEF及FVC差异无统计学意义(P>0.05);治疗后观察组患儿的FEV1、PEF及FVC明显低于对照组患儿,两组比较差异均有统计学意义(P<0.05);观察组患儿治疗总有效率为95.23%,对照组患儿治疗总有效率为73.81%,两组比较差异有统计学意义(P<0.05);观察组患儿治疗满意率为95.23%,对照组患儿治疗满意率为64.29%,两组比较差异有统计学意义(P<0.05)。结论氧驱雾化吸入普米克令舒治疗小儿哮喘急性发作患儿,能有效地改善患儿的喘憋以及咳嗽等症状,有效的改善患儿的肺功能,效果显著,值得临床推广使用。 Objective To explore the clinical effect of oxygen atomization inhalation of pulmicort in treatment of children with acute exacerbation of asthma and the impact on lung function.Methods Eighty-four children with acute exacerbation of asthma treated in the hospital were selected and randomly divided into observation group and control group,42 children in each group.The children in control group were treated by routine treatment,while the children in observation group were treated by oxygen atomization inhalation.After treatment,disappearance time of dyspnea,lung wheezing rales,wheezing,cough and hospitalization time in the two groups were observed.The improvement of lung function,clinical effects and satisfaction degrees in the two groups were compared.Results The disappearance time of dyspnea,lung wheezing rales,wheezing,and cough after treatment in observation group was statistically significantly shorter than those in control group,while the hospitalization time in observation group was statistically significantly shorter than that in control group(P〈0.05).Before treatment,there was no statistically significant difference in FEV1,PEF,and FVC between the two groups(P〈0.05).After treatment,FEV1,PEF,and FVC in observation group were statistically significantly lower than those in control group(P〉0.05).The total effective rates in observation group and control group were 95.23% and 73.81%,respectively,there was statistically significant difference between the two groups(P〈0.05).The satisfaction rates of patients in observation group and control group were 95.23% and 64.29%,respectively,there was statistically significant difference between the two groups(P〈0.05).Conclusion Oxygen atomization inhalation of pulmicort in treatment of children with acute exacerbation of asthma can effectively improve dyspnea,cough,and pulmonary function of these children,the effect is significant,and the method is worthy of clinical promotion and application.
出处 《中国妇幼保健》 CAS 2017年第6期1207-1210,共4页 Maternal and Child Health Care of China
基金 秦皇岛市科学技术研究与发展计划项目(201502A169)
关键词 小儿哮喘急性发作 氧驱雾化吸入 肺功能 普米克令舒 Child with acute exacerbation of asthma Oxygen atomization inhalation Pulmonary function Pulmicort
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