摘要
目的探讨抗Gp210阳性原发性胆汁性肝硬化(PBC)患者的临床特征。方法选取2014年1月—2016年12月在牡丹江市康安医院确诊的120例PBC患者,按照抗Gp210阳性、抗Gp210阴性将患者分成两个对照组,比较两组患者间肝功及血凝等主要指标的差异。结果该病主要累及中年女性,中位发病年龄为50岁左右,本研究病例也以女性患者为主。两组患者经生化及血凝等指标比对后发现,抗Gp210阳性PBC患者转氨酶、碱性磷酸酶、胆红素水平较高,而白蛋白、胆碱酯酶较低。结论在原发性胆汁性肝硬化患者中抗Gp210阳性者肝功能受损更为严重。
Objective To investigate the clinical features of patients with Gp210 positive primary biliary cirrhosis （PBC）. Methods 120 cases of PBC were selected from January 2014 to December 2016 in Mudanjiang Ankang Hospital, with positive anti Gp210, anti Gp210 negative patients were divided into two groups, the difference between the two groups of patients the main indicators of liver fimction and blood coagulation. Results The disease mainly involved middle-aged women, the median age of onset was about 50 years old. The two groups of patients after biochemical and blood coagulation index comparison found that anti Gp210 positive PBC patients with higher levels of transaminase, alkaline phosphatase, bilirubin, and albumin, cholinesterase lower. Conclusion In patients with primary biliary cirrhosis, the liver function of patients with anti Gp210 positive is more serious.
出处
《中国继续医学教育》
2017年第5期63-64,共2页
China Continuing Medical Education
