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TPOAb阳性对妊娠期妇女甲状腺功能及不良妊娠的影响 被引量:4

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摘要 目的探讨甲状腺过氧化物酶抗体(TPOAb)阳性对妊娠期妇女甲状腺功能及不良妊娠的影响。方法选取在该院接受产前检查的106例单胎孕妇,其中53例TPOAb阳性的孕妇为观察组,53例TPOAb阴性的孕妇为对照组。对比两组孕妇孕晚期甲状腺功能异常的发生率;同时对比两组孕妇不良妊娠事件和新生儿并发症的发生率。结果观察组单纯TSH升高的发生率为11.32%,甲状腺功能异常的发生率为26.42%,均显著高于对照组(均P<0.05);观察组不良妊娠事件发生率为32.08%,显著高于对照组(P<0.05);观察组吸入综合征发生率为15.09%,新生儿并发症发生率为24.53%,均显著高于对照组(均P<0.05)。结论妊娠早期TPOAb阳性的孕妇,妊娠晚期甲状腺功能异常的发生率显著增加,同时不良妊娠事件和新生儿并发症的发生风险也显著上升。临床应重视妊娠早期TPOAb的筛查。
出处 《国际检验医学杂志》 CAS 2017年第7期1001-1003,共3页 International Journal of Laboratory Medicine
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