摘要
目的:探讨口服布拉氏酵母菌预防早产儿抗生素相关腹泻病的临床效果。方法:选取98例肺炎和支气管肺炎的早产患儿作为研究对象,其中对照组(38例)患者予以使用抗生素治疗,当出现腹泻后予以补液和蒙脱石散处理,研究组(60例)患者予以抗生素同时口服布拉氏酵母菌散剂治疗,并比较两组患儿相关性腹泻发生率、腹泻持续时间和大便次数等。结果:研究组患儿发生抗生素相关性腹泻比例显著低于对照组,组间比较差异具有统计学意义(P<0.05);研究组患者腹泻持续时间、大便平均次数以及腹泻治疗效果均显著优于对照组,组间比较差异具有统计学意义(P<0.05)。结论:布拉氏酵母菌口服有助于减少或预防早产患儿抗生素相关性腹泻的发生以及缩短腹泻持续时间和减少大便次数,值得推广应用。
Objective： To investigate the clinical effect of oral administration of saccharomyces boulardii on antibiotic-related diarrhea in preterm infants. Methods： A total of 98 preterm infants with pneumonia and bronchopneumonia hospitalized in our hospital from January 2014 to December 2015 were enrolled in the study. The control group（ 38 patients） was treated with antibiotics,treated by rehydration and montmorillonite powder after the diarrhea. 60 cases in the study group were treated with antibiotics and oral administration of saccharomyces boulardii powder. The incidence of diarrhea,diarrhea duration and stool frequency were compared between the two groups. Results： The duration of diarrhea,mean number of stools and diarrhea were significantly higher in the study group than in the control group（ P〈0. 05）.The diarrhea duration,stool frequency and diarrhea were significantly lower in the study group than in the control group.There was significant difference between the two groups（ P〈0. 05）. Conclusions： Oral administration of saccharomyces boulardii can help to reduce or prevent the occurrence of antibiotic-associated diarrhea in infants with preterm delivery,which will shorten the duration of diarrhea and reduce the number of stools. This method is worthy of popularization and application.
出处
《山西职工医学院学报》
CAS
2017年第1期12-14,共3页
Journal of Shanxi Medical College for Continuing Education
关键词
抗生素相关性腹泻
早产儿
布拉氏酵母菌
临床效果
Antibiotic-associated diarrhea
preterm infant
saccharomyces boulardii
clinical effect
