摘要
目的探讨子宫内膜癌复发的影响因素,并制定相应的治疗方案。方法比较分析135例子宫内膜癌手术治疗后出现复发患者与同期就治但未出现复发的135例子宫内膜癌患者复发的危险因素,并进行Logistic多因素回归分析。结果病理分级、腹腔积液检测阳性、肌层浸润深度≥1/2、淋巴结转移、肉眼分型和宫旁转移与子宫后内膜癌复发相关(P<0.05);年龄、病理分期和病理类型与其复发无关(P>0.05)。Logistic回归分析得出病理分级、肌层浸润深度、腹腔积液细胞学和淋巴结转移是影响子宫内膜癌术后复发的高危因素(P<0.05)。术后采取合适的辅助治疗能够提高长期生存率。结论病理分级、肌层浸润深度、腹腔积液检测阳性和淋巴结转移是影响子宫内膜癌术后复发的高危因素。患者术后可选择适宜的辅助治疗,经常复查,及时处理、减少复发,提高术后生存率和生活质量。
Objective To analyze the risk factors influencing recurrence of endometrial cancer and corresponding treatment. Methods Compare age, pathological type and pathological classification, surgical pathological staging, peritoneal cytology positive, depth of muscular infiltration,lymph node metastasis and other indicators of 135 endometrial cancer patients with recurrence after surgery and 135 endometrial cancer patients without recurrence in the same period. Logistic muhifactor regression analysis were conducted. Results Pathological grade, peritoneal cytology positive, depth of muscular infiltration ≥ 1/2, lymph node metastasis,typing,and parametrial transfer were associated with recurrence of endometrial carcinoma. Aged, pathological staging and pathological types were not correlated to recurrence of endometrial carcinoma. Logistic regression analysis showed that the pathological classification, depth of muscular infiltration, peritoneal cytology positive and lymph node metastasis were risk factors affecting the recurrence of endometrial carcinoma. Appropriate postoperative adjuvant therapy could improve the long-term survival rate. Conclusion Pathology classification, depth of muscular infiltration, peritoneal cytology positive and lymph node metastasis are risk factors affecting the postoperative recurrence of endometrial carcinoma. Appropriate adjuvant therapy after surgery ,regular review, and timely treatment can reduce the recurrence, improve the postoperative survival rate and quality of life.
出处
《实用癌症杂志》
2017年第5期820-822,共3页
The Practical Journal of Cancer
关键词
子宫内膜癌
复发
影响因素
Endometrial cancer
Recurrence
Risk factors
