摘要
目的:探讨结直肠癌死亡相关危险因素、直接致死原因及中医药治疗。方法:选取2014年1月至2016年5月就诊于辽宁中医药大学附属医院肿瘤科的结直肠癌死亡患者45例,对性别、年龄、饮酒史、吸烟史、临床分期、有无转移及积液(包括胸腔积液、腹腔积液、盆腔积液)及患者末次入院时的理化检测(血红蛋白、白蛋白)、中医症状评分进行总结和分析。结果:肠癌死亡危险因素单因素分析显示,肿瘤的临床分期、吸烟史、是否转移、有无积液、血红蛋白、中医症状评分情况是影响肠癌患者死亡的危险因素。肿瘤的临床分期、是否转移、血红蛋白、中医症状评分情况是影响肠癌患者死亡的独立危险因素。直接致死原因:恶病质11例(占24.44%),出现该症后中位生存时间为152d;肠梗阻(包括不完全性肠梗阻)12例(占26.66%),出现该症后中位生存时间为64d;消化道出血9例(占20%),出现该症后中位生存时间为8d;其他(包括肝性脑病、离子紊乱、感染等)。末次入院中医药使用率为80%。结论:降低结直癌死亡危险,须早发现、早诊断、早治疗,尽早使用中医药辅助治疗对于改善患者的生活质量甚至延长生存期有着一定的临床意义。
Objective：To investigate the risk factors related tO death of colorectal cancer,the direct cause of death and treatment of traditional chinese medicine. Methods： We selected 45 patients died of colorectal cancer in the affiliated hospital of the liaoning university of traditional chinese medicine from January 2014 to May 2016. Sex, age, smoking history, drinking history, clinical stage, metastasis and effusion （including pleural effusion. Ascites,pelvic effusion）physical and chemical testing and patients last admission （hemoglobin,albumin）,TCM symptom score factors were summarized and analysis. Results：Analysis of death risk factors of colorectal cancer with single factor： tumor metastasis, clinical history of smoking, with or without effusion, hemoglobin, scores of TCM symptoms were the risk factors of colorectal cancer. Multivariate analysis of risk factors of death colon cancer：clinical staging of tumor,whether metastasis,hemoglobin,clinical symptoms score. Conditions were the independent risk factors of death in patients with colorectal cancer. The direct cause of death： 11 cases with cachexia （24.44%）, the the median survival time was 152d; 12 cases with intestinal obstruction （including incomplete intestinal obstruction, 26.66% ）, the median survival time was 64d ; 9 cases of gastrointestinal bleeding （20%）, the median survival time was 8d; the other （including hepatic en- cephalopathy, ion disorder, infection etc. ）.At the time of admission of chinese medicine was used in 36 cases（80% ）.Conclusion：To reduce colorectal cancer risk of death, we should accomplish early detection, early diagnosis, early treatment, early use of TCM therapy. It has a certain clinical significance for improving the quality of life of patients.
作者
郑晓佳
张宁苏
李夏平
Zheng Xiaojia Zhang Ningsu Li Xiapin(Liaoning University of Traditional Chinese Medicine ,Shenyang 110847,China Affiliated Hospital of Liaoning University of Traditional Chinese Medicine ,Shenyang 110032, China)
出处
《甘肃医药》
2017年第4期241-243,共3页
Gansu Medical Journal
关键词
结直肠癌
危险因素
中医药
colorectal cancer
risk factors
traditional chinese medicine
