摘要
目的探讨慢性化脓性中耳炎病原菌分布及药敏试验结果。方法收集100例慢性化脓性中耳炎患者资料,分析耳脓性分泌物的病原菌培养及药敏试验结果。结果 100例患者,35例分离出病原菌,占35.0%,铜绿假单胞菌与金黄色葡萄球菌检出率最高。铜绿假单胞菌对头孢哌酮敏感率为90.9%,而对于哌拉西林、头孢他定、阿米卡星、注射用亚胺培南西司他丁钠的敏感率均为100.0%。金黄色葡萄球菌对阿米卡星和阿莫西林的敏感率均为100.0%,而对于青霉素的耐药率高达90.0%。结论铜绿假单胞菌与金黄色葡萄球菌为慢性化脓性中耳炎患者的主要致病菌,临床需综合病原菌检验及药敏试验结果合理选择抗生素,预防抗生素滥用。
Objective To explore the distribution and drug susceptibility of pathogens in the pus of chronic suppurative otitis media.Methods 100 cases of patients with chronic suppurative otitis media were selected as the study subjects,the culture and drug sensitivity result of pathogenic bacteria in purulent secretion of ear were analyzed.Results 35 cases were isolated pathogenic bacteria,accounting for 35.0%,the detection rate of the streptococcus pneumoniae and staphylococcus aureus were the highest.Pseudomonas aeruginosa to cefoperazone sensitive rate was 90.9%,while for piperacillin,ceftazidime,Amikacin,injectable imipenem cilastatin sodium sensitive rate was 100.0%.The sensitivity of Staphylococcus aureus to Amikacin and amoxicillin was 100.0%,and the resistance rate to penicillin was up to 90.0%.Conclusion S.aureus,S.epidermis,Pseudomonas aeruginosa and Mycetozoan were the predominant species of pathogens in the pus of chronic suppurative otitis media.Each pathogen had different sensitive to different antibiotics.It is necessary to choose antibiotics based on the pathogens and drug susceptibility analysis in the treatment of children with chronic suppurative otitis media.
出处
《中国药物经济学》
2017年第4期113-115,共3页
China Journal of Pharmaceutical Economics
关键词
慢性化脓性中耳炎
病原菌分布
药敏实验
Chronic suppurative otitis media
Pathogenic bacteria distribution
Drug sensitivity test
