摘要
目的探讨输卵管梗阻再通术中臭氧的应用效果。方法经临床和实验室证实的输卵管梗阻患者116例,随机数字表法将患者分为研究组与对照组,每组各58例。所有患者住院期间均接受介入性输卵管再通术治疗。研究组应用臭氧水行输卵管灌注,而对照组则采用常规消炎及防粘连药物溶液。随访6个月,观察统计2组患者妊娠率及输卵管再闭塞率,同时于术后2周对2组患者不适症状进行评价并比较。结果研究组输卵管再通成功率为93.1%(54/58),妊娠率为79.3%(46/58),再发闭塞率为5.2%(3/58)。而对照组输卵管再通成功率为91.4%(53/58),妊娠率为60.3%(35/58),再发闭塞率为17.2%(10/58)。分析显示,2组患者再通成功率差异无统计学意义(P>0.05),但研究组妊娠率及再发闭塞率显著高于对照组,差异具有统计学意义(P<0.05)。研究组不适症状评分与对照组差异无统计学意义(P>0.05)。结论在输卵管再通术中采用臭氧灌注可有效提高术后妊娠率,降低再发闭塞。
Objective To evaluate the curative effect of fallopian tube perfusion with ozone water in treating obstructed fallopian tube in pluripara. Methods A total of 116 patients with distal fallopian tube obstruction were included in this study. The diagnosis was confirmed by clinical and laboratory materials. The patients were randomly divided into the study group and the control group with 58 patients in each group. During hospitalization period all patients received interventional recanalization therapy for obstructed fallopian tube. For the patients of the study group, ozone water perfusion of fallopian tube was employed, while for the patients of the control group, fallopian tube perfusion with conventional anti-inflammatory drug and anti- adhesion solution was adopted. All the patients were followed up for 6 months, the pregnancy rate and the fallopian tube re-occlusion rate of both groups were calculated, and 2 weeks after the treatment the patients＇ discomfort symptoms were evaluated. Results The success rate of fallopian tube recanalization, the pregnancy rate and the re-obstruction rate in the study group were 93.1% （54/58）, 79.3% （46/58） and 5.2% （3/58） respectively, which in the control group were 91.4% （53/58）, 60.3% （35/58） and 17.2% （10/58） respectively. Statistical analysis indicated that no significant difference in the success rate of fallopian tube recanalization existed between the two groups （P〉0.05）. The pregnancy rate of the study group was higher than that of the control group, while the re-obstruction rate in the study group was lower than that in the control group; the differences between the two groups were statistically significant （P〈0.05）. No significant differences in discomfort symptom scores existed between the two groups （P〉0.05）. Conclusion Fallopian tube perfusion with ozone water can be adopted for tubal recanalization, this technique can effectively improve the postoperative pregnancy rate and reduce the tubal re-obstruction rate.（J Intervent Radial, 2017, 26： 455-458）
出处
《介入放射学杂志》
CSCD
北大核心
2017年第5期455-458,共4页
Journal of Interventional Radiology
关键词
输卵管性不孕
输卵管梗阻
臭氧
介入治疗
tubal infertility
fallopian tube obstruction
ozone
interventional therapy
