摘要
目的:分析米非司酮周期疗法和孕激素治疗围绝经期功血的效果。方法:抽取笔者所在医院2015年4月-2016年6月收治的60例围绝经期功血患者,依据入院治疗的先后顺序分为观察组和对照组,对照组患者采用孕激素进行治疗,观察组患者采用米非司酮周期治疗方法,对两组患者的临床治疗效果进行评估。结果:观察组和对照组各自治疗前后,性激素水平以及子宫内膜厚度同组比较,差异均有统计学意义(P<0.05);两组患者用药后比较,观察组性激素水平优于对照组,但差异无统计学意义(P>0.05)。用药期间两组月经周期均在正常范围,且组间比较,差异无统计学意义(P>0.05)。两组间的复发率及子宫内膜厚度比较,观察组明显优于对照组,差异有统计学意义(P<0.05)。结论:米非司酮周期疗法和孕激素在治疗围绝经期功血患者时,均可达到较佳的临床治疗效果,创建正常的性激素水平调整月经周期,同时对子宫内膜厚度进行有效控制。但米非司酮周期疗法可降低患者的临床复发率,明显优于使用孕激素治疗,临床治疗效果更佳,建议推广使用。
Objective： To analyze the contrast effect of Mifepristone cycle therapy and progesterone on perimenopausal dysfunctional uterine bleeding. Method： 60 cases of perimenopansal dysfunctional uterine bleeding patients in our hospital from April 2015 to June 2016 were selected, according to the sequence treatment in our hospital were divided into observation group and control group, the control group was treated with progesterone treatment, the observation group were treated with Mifepristone cycle therapy.The clinical therapeutic effects of the two groups were evaluated.Result： The differences in the sex hormone levels and endometrial thickness of the observation group and control group between before treatment and after treatment were statistically significant（P〈0.05）.After treatment, the sex hormone levels of the observation group was better than that of the control group, but the difference was not statistically significant（P〉0.05）.The menstrual cycle of the two groups Were in normal range, and there was no statistically significant difference between the two groups（P〉0.05）.The differences in the recurrence rate and endometrial thickness between the two groups were statistically significant（P〈0.05）.Conclusion ： Mifepristone cycle therapy and progesterone can achieve the better clinical therapeutic effect in the treatment of perimenopansal uterine bleeding patients, establish normal sex hormone levels to adjust the menstrual cycle, and effectively control the endometrial thickness,However, Mifepristone cycle therapy can reduce the clinical recurrence rate of patients, signifieantly better than the use of progesterone treatment, the clinical treatment is better, it is recommended to promote the use.
出处
《中外医学研究》
2017年第15期110-111,共2页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
米非司酮周期疗法
孕激素
围绝经期功血
Mifepristone cycle therapy
Progesterone
Perimenopausal dysfunctional uterine bleeding
