摘要
随着肥胖的流行，与其相关的一系列代谢综合征的发生也呈现上升趋势。肥胖引起的慢性低度炎症状态参与各种代谢综合征的发生。而对于肥胖引起的慢性炎性反应的机制尚未完全阐明。肥胖通过活化多种信号通路介导炎性因子的产生与释放，造成机体的脂质代鲥紊乱、胰岛素的抵抗等，促进代谢性疾病的发生与进展。因而本文主要针对肥胖与慢性炎性反应之间可能相关机制的研究进展进行综述。
Metabolic syndrome is becoming increasingly prevalent among obese people. Obesity induced chronic low-grade inflammation is involved in various metabolic syndromes and the mechanism is under investigation. Obesity promotes production and release of inflammatory factors through activation of multiple signaling pathways, resulting in lipid metabolism disorder, insulin resistance and so on. This paper reviewed correlations between obesity and inflammation.
出处
《中国医药》
2017年第6期946-949,共4页
China Medicine
基金
陕西省科技厅社会发展科技攻关项目（2014SF2-11）
关键词
肥胖
炎症
代谢综合征
Obesity
Inflammation
Metabolic syndrome
