摘要
目的观察病理组织中嗜酸性粒细胞增多与否与CRS病情程度的相互关系,探讨根据嗜酸性粒细胞指导分型有无可行性。方法收集136例慢性鼻-鼻窦炎患者的临床资料,根据病理组织中嗜酸性粒细胞是否增多,分为嗜酸性粒细胞增多组和非嗜酸性粒细胞增多组,观察两组患者主观病情评估和鼻窦CT Lund—MacKay评分是否有差别。结果两组患者主观病情评估和鼻窦CT Lund-Mackay评分结果经统计学分析差异均无显著性。结论慢性鼻-鼻窦炎是一种复杂的、多因素作用引起的炎性疾病,嗜酸性粒细胞的浸润在慢性鼻-鼻窦炎的发病机制中并不占主导地位,可能是多因素共同作用参与其发病。单独依据嗜酸性粒细胞行慢性鼻-鼻窦炎的分型是不充分的,必须结合病理组织学特点与临床特征综合考虑。
Objective To investigate the relationship between the number of eosinophils in pathological tissues and the severity of CRS ,and to discuss whether the feasibility of eosinophil-based typing. Methods The clinical data of 136 patients with chronic rhinosinusitis were collected and divided into two groups,Eosinophilia group and non-eosinophil group, according to whether the increase of eosinophils in the pathological tissue. To observe whether the subjective condition evaluation and CT lund-MacKay score of the sinuses is different. Results There was no significant difference between the two groups in the subjective condition evaluation and the CT lund-Mackay score. Conclusion Chronic rhinosinusitis is a complex and multifactorial inflammatory disease. The infiltration of eosinophils is not a dominant factor in the pathogenesis of chronic rhinosinusitis. It may be a multifactorial interaction in the pathogenesis of chronic rhinosinusitis. Alone based on eosinophils in the classification of chronic rhinosinusitis is not sufficient, while the comprehensive consideration must be combined with histopathological characteristics and clinical features.
出处
《中国中西医结合耳鼻咽喉科杂志》
2017年第2期91-93,共3页
Chinese Journal of Otorhinolaryngology in Integrative Medicine
