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硫酸镁联合硝苯地平治疗重度子痫前期的应用优势探析 被引量:1

Application Advantage of Magnesium Sulfate Combined with Nifedipine in Treating Severe Preeclampsia
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摘要 目的分析硫酸镁联合硝苯地平治疗重度子痫前期的应用优势。方法将我院2014年2月~2016年1月收治的100例重度子痫前期患者作为研究对象,按随机数字表法将患者分为对照组和观察组,每组50例。对照组患者给予硫酸镁治疗,观察组患者采用硫酸镁联合硝苯地平治疗,观察比较两组患者的临床治疗效果。结果两组患者治疗前的血细胞压积、24h尿蛋白定量、血黏度比较,差异均无统计学意义(P>0.05);治疗后,观察组患者的各项指标均显著优于对照组,差异有统计学意义(P<0.05);两组的临床治疗总有效率比较,观察组为96.0%(48/50)高于对照组的82.0%(41/50),差异有统计学意义(P<0.05)。结论硫酸镁联合硝苯地平治疗重度子痫前期患者具有显著的临床疗效,能有效改善患者的血液指标,降低尿蛋白量,值得临床推广应用。 Objective To analyze application advantage of magnesium sulfate combined with nifedipine in treating severe preeclampsia.Methods 100 cases of patients with severe preeclampsia admitted in our hospital since February 2014 to January 2016 were selected as the object of study and were randomly divided into control group and experiment group with 50 cases for each.Patients in control group were treated with magnesium sulfate,while those in experiment group were treated with magnesium sulfate combined with nifedipine.Patients in two groups were compared for clinical effects via observation.Results There was no statistical significance in difference of hematocrit,24 h urine protein quantitation and blood viscosity between two groups before and after treatment (P〉0.05).After treatment,various indexes of patients in experiment group were dramatically superior to those in control group (P〈0.05).The total clinical treatment efficacy of control group and experiment group were 82.0%(41/50)and 96.0%(48/50)respectively.In the case of total clinical treatment efficacy,experiment group was significantly higher than control group (P〈0.05).Conclusion Magnesium sulfate combined with nifedipine has significant clinical efficacy in treating severe preeclampsia.It can effectively improve blood indexes,reduce urine protein for patients,which is worthy of clinical expansion and application.
作者 王庆玲
出处 《蛇志》 2017年第2期154-155,共2页 Journal of Snake
关键词 硫酸镁 硝苯地平 重度子痫前期 应用优势 Magnesium sulfate Nifedipine Severe preeclampsia Application advantage
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