摘要
利用Scifinder、ACS、CNKI及维普等数据库查阅近十年来国内外抗过敏天然产物研究相关报道,对不同结构类型的抗过敏天然产物进行总结。主要介绍了过敏性疾病的发病机制,抗过敏天然产物的活性部位、活性单体、来源及作用机制等方面。天然产物抗过敏作用靶点多,毒副作用小,但目前该方向的研究尚有不足之处,在此基础上提出抗过敏中药或天然药物研究的几个思路,为进一步研究抗过敏天然药物提供参考。
Based on overseas and domestic data bank mainly as Scifinder, ACS publication, CNKI, and CQVIP. The relationships between the types of natural products and their anti-allergic activities have been summarized. The advances of anti-allergic natural prod- ucts over the past ten years have been reviewed. The pathogenesis of allergic diseases and the diversity of anti-allergy components and natural products were summarized, together with their origins and mechanisms of anti-allergy activities. Many natural products show multiple anti-allergy targets and few side effects, while the research is still far from enough. Several suggestions were proposed for fur- ther research on anti-allergy natural medicines on the basis of our review.
出处
《中国药学杂志》
CAS
CSCD
北大核心
2017年第12期997-1004,共8页
Chinese Pharmaceutical Journal
基金
福建省高校青年自然基金重点项目(Z1625138)
华侨大学中青年教师科研提升资助计划(600005-Z15J0025)
华侨大学科研基金资助项目(600005-Z15Y0015)
华侨大学研究生科研创新能力培育计划资助项目
关键词
抗过敏
天然产物
化学结构
作用机制
anti-allergy
natural product
chemical structure
mechanism
