摘要
目的探讨D-二聚体检测对于糖尿病诊断的临床意义。方法选取选取该院收治的糖尿病患者80例,根据是否合并并发症将其分为两组,同时选择同期参与体检的健康志愿者50名作为对照,比较3组D-二聚体、纤维蛋白原以及糖化血红蛋白。结果糖尿病合并并发症组患者的D-D、Fib以及Hb Alc都显著高于糖尿病不合并并发症组患者、健康志愿者(P<0.05)。糖尿病不合并并发症组患者与健康志愿者在D-D、Fib的比较上差异无统计学意义(P>0.05),而Hb A1c的比较则有糖尿病不合并并发症组患者显著高于健康志愿者的情况(P<0.05)。结论通过D-二聚体的检测可以为糖尿病并发症的早期临床诊断提供依据,为病情的控制提供指导,值得临床推广应用。
Objective To study the clinical significance of D-dipolymer detection in the diabetes, Methods 80 cases of diabetes patients admitted and treated in our hospital were selected and divided into two groups according to the complications, and 50 cases of healthy physical examination volunteers at the same period were selected as the control group, and the D-dipolymer, fibrinogen and glycosylated hemoglobin were compared between the three groups. Results The D-D, Fib and HbAlc in the patients with diabetes with complications were obviously higher than those in patients with diabetes with-out complications and healthy volunteers （P〈0.05）, and the differences in the D-D and Fib between the patients with diabetes without complications and healthy volunteers（P〉0.05）, and the HbAlc in patients with diabetes without complications was higher than that of healthy volunteers （P〈0.05）. Conclusion The D-dipolymer detection can provide basis for the early clinical diagnosis of diabetic complications and provide guidance for the control of diseases, which is worth clinical promotion and application.
作者
陈智阳
黄江山
陈芒好
CHEN Zhi-yang HUA NG Jiang-shan CHEN Mang-hao(Department of Clinical Laboratory, First Affiliated Hospital of Xiamen University Siming Branch, Xiamen, Fujian Province, 361003 China)
出处
《糖尿病新世界》
2017年第7期73-74,77,共3页
Diabetes New World Magazine
关键词
D-二聚体
糖尿病
临床意义
D-dipolymer
Diabetes
Clinical significance
