摘要
目的探讨医院鲍曼不动杆菌临床分布、标本来源及其耐药性。方法回顾性分析医院鲍曼不动杆菌感染患者227例的临床资料。统计分析鲍曼不动杆菌来源、病区分布及耐药性。结果共分离出鲍曼不动杆菌227株,其中分离出最多的科室是ICU,其次是神经内科、神经外科。鲍曼不动杆菌主要来源于痰标本、纤支镜灌洗液、尿液,且均对临床常用抗菌药物有较高的耐药性。鲍曼不动杆菌对氨苄西林/舒巴坦敏感率高于派拉西林/他唑巴坦。结论该院ICU住院患者感染鲍曼不动杆菌的风险最高,且多见耐药菌株。含舒巴坦的β-内酰胺抗菌药物对此类感染有较好疗效。
Objective To investigate the clinical distribution,drug source and drug resistance of Acinetobacter baumannii in hospital. Methods A retrospective analysis of 227 cases of Acinetobacter baumannii infection based on clinical data. Conducting a statistical analysis of Acinetobacter baumannii origin,Ward distribution and drug resistance. Results A total of 227 strains of Acinetobacter baumannii were isolated,of which the most isolated departments were ICU,followed by neurology,neurosurgery. Acinetobacter baumannii are mainly from the sputum specimens,bronchoscopy lavage fluid,urine,and have a higher level of resistance to the commonly used clinical antibiotics. The sensitivity of ampicillin to ampicillin/sulbactam was higher than that of paclitaxel/tazobactam. Conclusion Patients in ICU has the highest risk of infecting Acinetobcter baumannii with the drug resistance. Antibiotics that combines with β-lactam antibiotics and sulbactam potentially provides a useful therapy in hospital.
出处
《临床合理用药杂志》
2017年第20期1-3,共3页
Chinese Journal of Clinical Rational Drug Use
关键词
鲍曼不动杆菌
感染
耐药性
舒巴坦
Acinetobacter baumannii
Infection
Drug resistance
Subactam
