摘要
[目的]观察逍遥散联合氟哌噻吨美利曲辛与奥美拉唑治疗肝郁脾虚功能性消化不良疗效。[方法]使用随机平行对照方法,将60例门诊患者按随机数字表方法简单随机分为两组。对照组30例氟哌噻吨美利曲辛,1粒/次,1次/d,口服;奥美拉唑,1粒/次,1次/d,晨起或睡前空腹口服。治疗组30例逍遥散,8粒/次,3次/d,口服;西药治疗同对照组。连续治疗4周为1疗程。观测临床症状、焦虑抑郁积分(SAS、SDS)、不良反应。治疗1疗程(4周),判定疗效。[结果]治疗组痊愈9例,显效10例,有效7例,无效4例,总有效率86.67%;对照组痊愈2例,显效7例,有效10例,无效11例,总有效率63.33%;治疗组疗效优于对照组(P<0.05)。SAS积分两组均有改善(P<0.01),治疗组改善优于对照组(P<0.01),SDS积分治疗组明显改善(P<0.01),对照组无明显变化(P>0.05)。[结论]逍遥散联合氟哌噻吨美利曲辛与奥美拉唑治疗肝郁脾虚功能性消化不良,疗效满意,无严重不良反应,值得推广。
[Objective] Observation of Xiaoyao Powder Combined with Flupentixol and melitracen and omeprazole in the treatment of liver stagnation and spleen deficiency of functional dyspepsia. [Method] 60 cases of outpatients were randomly divided into two groups according to random number table method. The control group of 30 cases of Flupentixol and rnelitracen tablets, 1 tablets, 1 times/d, oral; omeprazole, 1 tablets, 1 times/d, oral fasting morning or before going to bed. The treatment group of 30 cases of Xiaoyao Powder,/times, 3 times/d, oral, western medicine treatment with the control group. Continuous treatment for 4 weeks for a course of 1. Clinical symptoms, anxiety and depression scores （SAS, SDS）, adverse reactions. Treatment for 1 courses （4 weeks）, determine the efficacy. [Results] the treatment group 9 cases were cured, 10 cases markedly effective, 7 cases effective, 4 cases ineffective, the total efficiency of 86.67%; control group 2 cases were cured, 7 cases markedly effective, 10 cases effective, 11 cases ineffective, the total efficiency of 63.33%; the treatment group than the control group （P〈0.05）. SAS score of two groups were improved （P〈0.01）, the treatment group was better than the control group （P〈0.01）, SDS integral treatment group was significantly improved （P〈0.01）, the control group had no significant change （P〉0.05）. [Conclusion] Xiaoyaosan combined with flupentixol and melitracen and omeprazole in the treatment of liver stagnation and spleen deficiency of functional dyspepsia, satisfactory curative effect, no serious adverse reactions, worthy of promotion.
出处
《实用中医内科杂志》
2017年第7期50-52,共3页
Journal of Practical Traditional Chinese Internal Medicine
关键词
功能性消化不良
胃脘痛
痞满
嘈杂
肝郁脾虚
逍遥散
氟哌噻吨美利曲辛
奥美拉唑
焦虑抑郁积分(sAs、SDS)
中西医结合治疗
随机平行对照研究
functional dyspepsia
stomachache
fullness
noise
liver stagnation and spleen deficiency
Xiaoyaosan
flupentixol united tysin
omeprazole
anxiety depression score （SAS, SDS）
integrated traditionalChinese and western medicine therapy
randomized controlled study
