摘要
目的:探讨高乌甲素超前镇痛对妇科腹腔镜术后镇痛影响。方法:60例ASAI-Ⅱ级择期行妇科腹腔镜病人,随机分为两组,每组30例,A组在气管插管后静注高乌甲素0.15mg/kg。B组在手术结束时静注高乌甲素0.15mg/kg。两组患者术毕清醒后均静注芬太尼1ug/kg用于术后镇痛。分别记录术后4、6、8、24小时视觉模拟评分(VAS)并记录麻醉时间,麻醉苏醒及不良反应等情况。结果:A组在术后4、6、8、24小时VAS低于B组(P<0.05),两组患者麻醉时间比较差异无统计学意义,两组患者从手术结束到呼之睁眼时间相似。B组需追加哌替啶行术后镇痛患者数明显多于A组(P<0.05),两组均无明显的不良反应。结论:高乌甲素0.15mg/kg超前镇痛可以产生较好的镇痛效果以及可减少阿片药的用量,同时不影响麻醉恢复。
Objective To investigate the effects of lappaconitine preemptive analgesia on the gynecological laparoscopy postoperative analgesia.Methods 60 cases ASAI-Ⅱ-level elective gynecological laparoscopic patients were randomly divided into two groups with 30 cases each.A tracheal intubation in the group after the intravenous injection of a lappaconitine 0.15 mg / kg..Group B,in operation at the end of a lappaconitine intravenous 0.15 mg / kg.Sober in the two groups after the completion of intravenous fentanyl 1 ug / kg for postoperative analgesia.Were recorded hours after 4,6,8,24 visual analogue score(VAS) and record anesthesia,anesthesia and recovery adverse reactions,such as the outcome of Group.Results A in the hours after 4,6,8,24 VAS lower than in group B(P<0.05) compared two groups of patients anesthesia time difference was not statistically significant,from the end of operation in the two groups to call a time similar to eyes open,B group needed additional pethidine postoperative analgesia significantly more than patients in group A(P<0.05) There were no significant adverse reactions.Conclusion Concluded of lappaconitine 0.15 mg / kg preemptive analgesia can produce better analgesic effect and could reduce the amount of opioid drugs,anesthesia at the same time not affect the resumption.
出处
《湖南师范大学学报（医学版）》
2009年第1期35-37,共3页
Journal of Hunan Normal University(Medical Sciences)
关键词
高乌甲素
超前镇痛
妇科腹腔镜手术
Lappaconitine
preemptive analgesia
gynecological laparoscopic surgery
