摘要
目的探讨多发性腔隙脑梗死痴呆疾病临床影响因素的影像学诊断应用价值,以及临床意义。方法择取2013年2月-2015年4月灵宝市第一人民医院收治的46例多发性腔隙脑梗死患者的临床病例记录资料展开回顾性分析。全面统计分析患者的临床症状和影像学表现特征。结果本组46例患者均满足多发性腔隙脑梗死痴呆的临床诊断标准,且在患病期间均出现不同程度的精神性临床症状和神经性临床症状。从发病时点角度分析,绝大多数患者在多发性腔隙脑梗死2次或者是2次以上发病条件下继发痴呆,患者通常在5年内复发腔隙性脑梗死,患者的病理组织,大多集中分布于基底节区、腇囊前核、膝关节部位及其周围、尾状核、豆状核、上下丘脑区,以及两侧脑室旁卵园区等,在患者的额叶、颞叶,以及顶叶皮质下方的白质性生理区域内部,通常会出现较多数量的斑点式或者是点状式的低密度病灶。结论多发性腔隙脑梗死痴呆患者通常会表现出一系列的神经性和精神性临床症状,且随着患者腔隙性脑梗死发病次数的不断增加,患者发生痴呆的可能性也会逐渐提升,针对已经发生腔隙性脑梗死后痴呆的患者做好针对性的治疗干预和预防处置,对于有效改善和提升患者的治疗效果和生存质量,具有充分价值,应当引起广泛关注。
Objective To investigate the imaging diagnosis value and clinical significance of dementia due to multiple lacunar infarction. Methods The clinical data of 46 patients with multiple lacunar infarction who were treated in our hospital from February 2013 to April 2015 were selected and analyzed retrospectively. The clinical symptoms and imaging features of patients were analyzed statistically. Results 46 cases of patients in the group were all consistent with the clinical diagnostic criteria of dementia due to muhiple lacunar infarction, and in the duration of the disease, there were different degrees of clinical symptoms and neurological symptoms in patients. From the point of view of onset, the vast majority of patients with secondary dementia were in the condition of multiple lacunar infarction occurred 2 times or more than 2 times. The recurrence of lacunar infarction usually occurred within 5 years. The pathological tissues of patients were mostly distributed in the basal ganglia, anterior capsule, empress knee joint and its surroundings, caudate nucleus, lentiform nucleus, paraventricular hypothalamic area, and both sides of egg park, etc. In the frontal lobe, temporal lobe, and white matter physiological region under the parietal cortex of the patients, there were usually a large number of low density lesions with speckled or punctate type. Conclusion Patients with dementia due to multiple lacunar infarction typically exhibit a range of neurological and psychiatric symptoms, and with the occurrence of lacunar infarction increasing, patients are more likely to occur dementia. It is of great value to provide targeted intervention and prevention in patients who have occurred dementia due to multiple lacunar infarction, and it can improve the therapeutic effect and quality of life of patients, which should be widely concerned.
出处
《新疆医学》
2017年第6期609-611,共3页
Xinjiang Medical Journal
关键词
多发性腔隙脑梗死痴呆
相关因素
影像学诊断价值
临床研究
Dementia due to multiple lacunar infarction
Related factors
Imaging diagnostic value
Clinical research
