摘要
目的探讨细节管理联合常规管理在脑出血患者脑保护剂治疗中的管理效果及对认知功能的影响。方法选取2016年1月~2016年12月本院收治的脑出血患者150例,随机分为2组,每组75例。对照组应用脑保护剂奥拉西坦治疗,研究组联合应用细节管理以及常规管理,观察比较2组患者管理效果以及认知功能。结果研究组患者治疗效果显著优于对照组（P〈0.05）;治疗前,2组患者的TIMP-1（基质蛋白酶抑制剂-1）以及MMP-9（血浆基质蛋白酶-9）指标差异无统计学意义,治疗后均得到一定改善,且研究组显著优于对照组（P〈0.05）;治疗前,2组患者的BI指数、神经功能以及认知功能对比差异无统计学意义,治疗后均得到一定改善,且研究组显著优于对照组（P〈0.05）。结论脑出血患者脑保护剂治疗过程当中,联合应用细节管理以及常规管理有利于提高治疗效果,改善患者认知功能。
Objective To investigate the management effect of detail management combined with routine management in the treatment of cerebral protective agent in patients with cerebral hemorrhage and its effect on cognitive function. Methods 150 cases of patients with cerebral hemorrhage admitted in our hospital from January 2016 to December 2016 were randomly divided into two groups,75 cases in each groups. The control group was treated with the brain protectant olanxetan,the study group used the detailed management and routine management. Observation and comparison of two groups of patients with management and cognitive function. Results The treatment effect of the study group was significantly better than that of the control group（ P 〈0. 05）. Before treatment,the difference of TIMP-1 and MMP-9 between the two groups was not statistically significant,after treatment were improved,and the study group was significantly better than the control group（ P〈 0. 05）. There was no significant difference in BI index,neurological function and cognitive function between the two groups before treatment,and the treatment group was significantly improved after treatment,and the study group was significantly better than the control group（ P〈 0. 05）. Conclusion The combination of detailed management and routine management is helpful to improve the therapeutic effect and improve the cognitive function of patients with cerebral hemorrhage.
出处
《中国生化药物杂志》
CAS
2017年第7期421-423,共3页
Chinese Journal of Biochemical Pharmaceutics
关键词
细节管理
常规管理
脑出血
脑保护剂
认知功能
detail management
routine management
cerebral hemorrhage
brain protectors
cognitive function
