摘要
目的了解济南地区中老年人群维生素D的营养状况,并探讨其与血脂的关系。方法随机抽取2014年7月至2016年6月间山东大学附属省立医院体检的453例中老年人为研究对象,其中中年组107例,老年组346例,男性317例,女性136例。采用罗氏电化学发光免疫分析仪测定中老年人群血清25-羟维生素D(25-OHVit D)水平,Beckman AU5800全自动生化分析仪测定血脂指标(总胆固醇、甘油三脂、低密度脂蛋白胆固醇、高密度脂蛋白胆固醇),并分析25-OHVit D水平与年龄、性别、季节及血脂的关系。结果 (1)中年组人群维生素D不足占54.21%,明显高于老年组的42.77%;中年组维生素充足占6.54%,明显低于老年组的13.58%,差异均有统计学意义(P<0.05);(2)在夏季,中老年人血清25-OHVit D不足占36.10%,明显低于春季的49.58%和秋季的58.82%,差异均有统计学意义(P<0.05);(3)25-OH Vit D水平缺乏和不足(<20 ng/m L)时,血清25-OH Vit D与甘油三酯呈负相关(r=-0.350,P<0.01)。结论济南地区中老年人群维生素D缺乏及不足比较普遍,在夏季维生素D不足状况有改善,维生素D缺乏不足与血清甘油三脂有关。
Objective To explore the Vitamin D nutritional status and the relationship between Vitamin D and blood lipid levels in middle-aged and elderly people of urban residents in Jinan. Methods A total of 453 middle-aged and elderly people undergoing physical examination in our hospital from Jul. 2014 to Jun. 2016, including 107 middleaged and 346 elderly people, 317 men and 136 women, were selected by a random sampling. Serum 25-hydroxy vitamin D（25-OHVit D） level was measured by Roche electro chemiluminescence immunoassay analyzer, and blood lipid indexes（triglyceride [TG], total cholesterol [TC], high-density lipoprotein cholesterol [HDL-C] and low-density lipoprotein cholesterol [LDL-C]） were detected by Beckman AU5800 automatic biochemical analyzer. The relationships between25-OHVit D levels and ages, gender, season and blood lipid levels were analyzed. Results The percent of Vitamin D insufficiency or sufficiency showed statistical difference in middle-aged people and in elderly people（54.21% vs 42.77%for insufficiency; 6.54% vs 13.58% for sufficiency; both P〈0.05）. The percent of Vitamin D insufficiency in summer was significantly lower than that in spring or autumn（36.10% in summer vs 49.58% in spring or 58.82% in autum, both P〈0.05）. People with less than 20 ng/m L 25-OHVit D showed a negative correlation between 25-OHVit D level and TG（r=-0.350, P〈0.01）. Conclusion Vitamin D deficiency and insufficiency are widely prevalent in Jinan residents, and Vitamin D showed increased levels in summer. People with the deficiency of 25-OHVit D showed negative correlation between 25-OHVit D level and TG.
出处
《海南医学》
CAS
2017年第14期2294-2296,共3页
Hainan Medical Journal
基金
国家自然科学基金(编号:81000731)
山东省优秀中青年科学家奖励基金(编号:B2010YY045)
关键词
济南
25-羟维生素D
中老年人群
维生素D缺乏
甘油三脂
相关性
Jinan
25-hydroxy vitamin D（25-OHVit D）
The middle-aged and elderly people
Vitamin D deficiency
Triglyceride（TG）
Correlation
