摘要
特发性肺纤维化是一种发病机制不明,致死致残率极高且目前临床疗效欠佳,是医疗界的棘手难题。在对IPF长期临床观察和实验研究下,发现该病同时存在着肺痹与肺痿的病机特点。从气机变化理论分析,在疾病的早期当属肺痹,以肺卫气虚、宗气不足、肺络痹阻为主要特点;在疾病的中晚期以肺痿为主,脾肾气虚、痰瘀胶结、络虚不荣;在疾病的慢性迁延期,存在着肺痹与肺痿的相互转化,不过痹与痿的侧重不同而已。
Idiopathic pulmonary fibrosis is a disease of unknown pathogenesis,high mortality rate and the current clinical efficacy is poor. It is a difficult problem in the medical community. Based on the long-term clinical observation and experimental study of IPF at the same time,it is found the disease pathogenesis has characteristics of lung flaccidity and consumptive lung disease. Theoretical analysis on the change of Qi movement,the early stage belongs to lung flaccidity,lung Weiqi deficiency,Zongqi deficiency,lung channels and collaterals obstruction. The late stage of the disease mainly belongs to consumptive lung disease,deficiency of spleen and kidney,phlegm and blood stasis,channels and collaterals failing to be nourished. In the stage of chronic migration,lung flaccidity and consumptive lung disease are mutual transformation but with different emphasis on stagnation and flaccidity.
出处
《中华中医药学刊》
CAS
北大核心
2017年第9期2332-2334,共3页
Chinese Archives of Traditional Chinese Medicine
基金
国家自然科学基金项目(81360581)
云南省应用基础研究计划项目(2013FZ251)
云南省青年基金项目(2014FD100)
关键词
特发性肺间质纤维化
中医
气机
肺痹
肺痿
idiopathic pulmonary fibrosis
TCM
Qi movement
lung obstruction
lung flaccidity
