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彩色多普勒超声联合超声弹性成像评价乳腺癌新辅助化疗疗效的研究 被引量:10

A research on the assessment of color Doppler ultrasound combined with ultrasonic elastography for curative effect of neoadjuvant chemotherapy for breast cancer
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摘要 目的:研究彩色多普勒超声联合超声弹性成像评价乳腺癌新辅助化疗疗效的价值。方法:选择在医院就诊行新辅助化疗(NAC)的100例乳腺癌患者,按照NAC后所应用的检查方法将其分为观察组和对照组,每组50例。对照组采用单纯彩色多普勒超声进行检查;观察组在彩色多普勒超声的基础上结合弹性成像技术进行检查。比较两组对乳腺癌NAC疗效鉴别诊断的准确率、灵敏度和特异度。结果:观察组对乳腺癌NAC疗效鉴别诊断准确度、灵敏度和特异度分别为88.00%,90.00%和86.00%;对照组对乳腺癌NAC疗效鉴别诊断准确度、灵敏度和特异度分别为78.00%、80.00%和76.00%;两组比较差异有统计学意义(x^2=2.01,x^2=3.24,x^2=3.45;P<0.05)。结论:彩色多普勒超声联合弹性成像从组织软硬度和血供两个方面对于乳腺癌患者NAC疗效进行诊查评价,与单纯使用彩色多普勒超声方法检查比较,更能够提高对评价乳腺癌NAC疗效的准确性。 Objective:To evaluate the value of color Doppler ultrasound combined with ultrasonic elastography for curative effect of neoadjuvant chemotherapy (NAC) for breast cancer.Methods: 100 patients with breast cancer who has received NAC were divided into observation group (50 cases, underwent examination of color Doppler ultrasound scanner combined with ultrasonic elastography) and control group (50 cases, only underwent examination of color Doppler ultrasound scanner) according to the different examination methods. The accuracy, sensitivity and specificity of differential diagnosis methods for curative effect of NAC between the two groups were compared as above data.Results: The accuracy, sensitivity and specificity of differential diagnosis for curative effect of NAC in observation group were 88.00%, 90.00% and 86.00%, respectively. While them of control group were 78.00%, 80.00% and 76.00%, respectively. And the differences of these indicators between the two groups were statistically significant (x2=2.01,x2=3.24,x2=3.45, P〈0.05).Conclusions: Color Doppler ultrasound combined with ultrasound elastography can diagnose the curative effect of NAC for patients with breast cancer from two aspects which includes tissue hardness and blood supply, and it can achieve more diagnostic accuracy compared with only using simple color Doppler ultrasound.
出处 《中国医学装备》 2017年第9期74-77,共4页 China Medical Equipment
关键词 乳腺癌 彩色多普勒超声 超声弹性成像 新辅助化疗 Breast cancer Color Doppler ultrasonography Ultrasonic elastography Neoadjuvant chemotherapy
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