摘要
目的研究瑞芬太尼联合丙泊酚靶控输注全身麻醉(全麻)对高龄妊娠剖宫产术产妇及新生儿的影响。方法将2014年2月至2016年8月该院收治的接受剖宫产术的120例高龄妊娠产妇采用随机数字表法分为观察组和对照组,每组60例。观察组术中给予靶控输注瑞芬太尼和丙泊酚,对照组术中给予靶控输注丙泊酚和间断静脉推注芬太尼。比较两组产妇术中心率(HR)和平均动脉压(MAP)的变化及新生儿Apgar评分。结果观察组产妇诱导时、胎儿娩出时HR均明显低于术前,对照组产妇诱导时、胎儿娩出时、胎儿娩出后5 min时HR均明显低于术前,差异均有统计学意义(P<0.05);观察组产妇胎儿娩出时、胎儿娩出后5 min时MAP均明显高于对照组,诱导后3 min、胎儿娩出时、胎儿娩出后5 min时HR均明显高于对照组,胎儿娩出后5 min时新生儿Apgar评分明显高于对照组,差异均有统计学意义(P<0.05)。结论应用瑞芬太尼联合丙泊酚靶控输注实施全麻对高龄妊娠产妇影响较小,同时对新生儿无明显影响。
Objective To investigate the effects of remifentanil combined with propofol target controlled infusion general anesthesia on maternal and infant in older pregnancy cesarean section. Methods One hundred and twenty cases of older pregnancy receiving cesarean section in this hospital from February 2014 to August 2016 were divided into the observation group and control group according to the random number table method,60 cases in each group. The observation group was intraoperatively given remifentanil combined with propofol by target-controlled infusion,while the control group was given propofol by targetcontrolled pumping and fentanyl by intermittently intravenous injection. The changes of intraoperative heart rate（HR） and mean arterial pressure（MAP） of parturients and neonatal Apgar scores were compared between the two groups. Results HR at induction and fetal delivery in the parturients of the observation group was significantly lower than that before operation（P〈0.05）. HR at induction,fetal delivery and at 5 min after fetal delivery in the parturients of the control group was significantly lower than that before operation,the differences were statistically significant（P〈0.05）. MAP at fetal delivery,at 5 min after fetal delivery in the parturients of the observation group was significantly higher than that in the control group,while HR at 3 min after induction,fetal delivery and 5 min after fetal delivery in the parturients of the observation group was significantly higher than that in the control group（P〈0.05）.The fetal Apgar score at 5 min in the observation group was significantly higher than that in the control group,the difference was statistically significant（P〈0.05）. Conclusion Remifentanil combined with propofol target controlled infusion for implementing general anesthesia has little influence on older pregnant women,meanwhile has no influence on newborn.
出处
《现代医药卫生》
2017年第19期2907-2908,2911,共3页
Journal of Modern Medicine & Health
关键词
年龄因素
妊娠
麻醉
全身
剖宫产术
Age factors
Pregnancy
Anesthesia
general
Cesarean section
