摘要
目的探讨促性腺激素释放激素（GnRH-a）联合腹腔镜手术对子宫内膜异位症的临床疗效。方法将140例子宫内膜异位症患者随机分为两组，对照组患者给予腹腔镜手术联合孕三烯酮治疗，实验组患者给予腹腔镜手术联合GnRH-a治疗，比较两组患者治疗前后腹痛、疾病症状评分、围绝经期症状、复发、不良反应与妊娠率。结果实验组患者治疗后SF-MPQ-2评分与AFS评分组间比较均显著性低于对照组；治疗后潮热出汗与骨关节痛评分组间比较均显著性低于对照组，差异有统计学意义（P〈0．01）；不良反应发生率明显低于对照组，差异有统计学意义（P〈0．05）。结论GnRH-a联合腹腔镜手术对子宫内膜异位症的临床疗效显著，具有借鉴意义。
Objective To investigate the clinical effect of gonadotropin releasing hormone （ Gn- RH-a） bombined with laparoscopic surgery on endometriosis. Methods One hundred and forty patients with endometriosis randomly divided into two groups. The patients in the control group were treated with laparoscopic surgery and gestrinone. The patients in the experimental group were given laparoscopy operation and GnRH-a treatment. The abdominal pain, disease symptom score, perimenopausal symptom, re-lapse, side effects and pregnancy rates before and after treatment were compared between the two groups. Results Compared with the control group, the scores of SF-MPQ-2 and AFS in the experimental group were significantly lower than those in the control group. The hot flashes and osteoarthritis scores in the ex- perimental group were lower than those in the control group （P 〈 0. 01 ）. The incidence of side effects was significantly lower in the experimental group than that of the control group （P 〈 0. 05 ）. Conclusions The clinical efficacy of GnRH-a combined with laparoscopic surgery on endometriosis is significant, and it has reference significance.
作者
张晓波
Zhang Xiaobo(Department of Gynaecology, the People＇ s Hospital of Laizhou, Laizhou 261400, China)
出处
《中国实用医刊》
2017年第18期75-77,共3页
Chinese Journal of Practical Medicine
