摘要
目的观察经鼻高流量湿化氧吸入疗法对不同海拔地区急性低氧性呼吸衰竭(AHRF)的疗效。方法广东省湛江市和西藏自治区林芝市45例AHRF患者随机分为平原地区中(n=12)、高流量组(n=12)及高原地区中(n=11)、高流量组(n=10),监测治疗后2 h、6 h、12 h、24 h呼吸频率、血气分析、血流动力学、舒适度。结果与其他3组比较,高原地区高流量组各时间点呼吸频率、心率及6 h、24 h血氧饱和度、氧合指数、动脉血氧分压均有明显改善(P<0.05)。各组患者舒适度差异无统计学意义(Hc=3.24,P>0.05)。结论经鼻高流量湿化氧吸入疗法是治疗高原地区AHRF较好方法。
Objective To observe the therapeutic efficacy of high-flow nasal cannula humidification oxygen therapy for acute hypoxic respiratory failure （AHRF） in different altitude districts. Methods Forty-five patients with AHRF collected from Zhanjiang city of Guangdong province and Linzhi city of Tibet Autonomous Region were randomized to medium （n= 12） and high （n=12） flow groups in plain district, and medium （n=l 1） and high （n=10） flow groups in plateau district. Respiratory rate, blood gas analysis, and hemodynamics parameters at 2 h, 6 h, 12 h, and 24 h post-therapy, and patient＇s comfortability were monitored in all groups. Results Compared with other groups, respiratory and heart rates at all time points, and blood oxygen saturation, oxygenation index and arterial PaO2 at 6 h and 24 h post-therapy were improvable in high flow group in plateau district （P〈0.05）. The patient＇s comfortability was comparable among all groups （Hc=3.24, P〉0.05）. Gonclusion The high-flow nasal cannula humidification oxygen therapy is effective for AHRF in plateau district.
出处
《广东医科大学学报》
2017年第4期398-401,共4页
Journal of Guangdong Medical University
关键词
湿化氧吸入
急性呼吸衰竭
高原地区
humidified oxygen inhalation
acute respiratiory failure
plateau district
