摘要
目的比较不同潮气量对机械通气患者呼吸机相关性肺炎(VAP)发生率及其预后的影响。方法选择2014年1月-2016年10月入住呼吸监护室(RICU)接受气管插管机械通气的患者32例,随机分为小潮气量[潮气量(VT):6~8 ml/kg]组(A组)和传统潮气量(VT:10~12 ml/kg)组(B组),每组16例,均采用压力调节容量控制-同步间歇指令通气+压力支持通气(PRVC-SIMV+PSV)模式通气,比较2组患者机械通气时间、VAP发生率、机械通气后VAP发生时间、RICU住院时间及28 d病死率。结果 A组机械通气时间和RICU住院时间长于B组,VAP发生率高于B组,VAP发生时间早于B组,差异均有统计学意义(P<0.05)。2组28 d病死率比较差异无统计学意义(P>0.05)。结论应用传统潮气量机械通气可有效预防VAP的发生并改善其预后。
Objective To compare the prevention and prognosis of ventilator associated pneumonia（VAP） under different tidal volume ventilations in rats.Methods A prospective study was conducted,32 intubated cases admitted to department of respiratory intensive care unit（RICU） from January 2014 to December 2016 were involved in the study.The patients were divided into two equal groups：low tidal volume group（tidal volume 6~8 ml/kg） and conventional tidal volume group（tidal volume 10~12 ml/kg）.The duration of mechanical ventilation,the incidence rate of VAP,the average time between intubated and occurrence of VAP and the length of RICU stay were compared among two groups.Results A group of mechanical ventilation time and RICU hospital stay longer than B group,the incidence of VAP was higher than that of B group,VAP occurred earlier than B group,the difference was statistically significant（P0.05）.There was no significant difference in the mortality rate between the two groups at 28 days（P0.05）.Conclusion Conventional tidal volume mechanical ventilation can effectively prevent the occurrence of VAP and improve its prognosis.
出处
《临床合理用药杂志》
2017年第28期37-38,共2页
Chinese Journal of Clinical Rational Drug Use
关键词
呼吸机相关性肺炎
潮气量
机械通气
Ventilator-associated Pneumonia
Tidal volume
Mechanical ventilation
