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胸腔镜下肺癌根治术治疗早期非小细胞肺癌的效果及预后 被引量:24

Effects and prognosis of thoracoscopic radical resection of pulmonary carcinoma for patients with early non-small cell lung cancer
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摘要 目的探究胸腔镜下肺癌根治术治疗早期非小细胞肺癌(NSCLC)患者对临床效果、并发症及预后的影响。方法选取2015年4月~2016年4月内蒙古医科大学附属医院胸外科收治的116例早期NSCLC患者临床资料进行分析,将其依据不同术式分成对照组(58例)与研究组(58例)。对照组行常规开胸肺癌根治术,研究组行胸腔镜下肺癌根治术,比较两组临床指标、并发症发生率以及生活质量评分情况。结果两组淋巴结清扫量差异无统计学意义(P>0.05)。研究组术中出血量、引流管置放时间、术后24 h VAS评分、住院时间均优于对照组,差异有高度统计学意义(P<0.01);研究组并发症总发生率显著低于对照组,差异有高度统计学意义(P<0.01);研究组生活质量评分中,功能状况、情感状况、身体状况、社会/家庭状况均高于对照组,差异有高度统计学意义(P<0.01)。结论胸腔镜下肺癌根治术能提高早期NSCLC疗效,且术后并发症少,安全性高,预后佳,具有临床推广及应用价值。 Objective To explore the effects of thoracoscopic radical resection of pulmonary carcinoma on the clinical effects, complications and prognosis in the treatment of early non-small cell lung cancer (NSCLC). Methods The clinical data of 116 patients with early NSCLC who had been seeking treatment in the Affiliated Hospital of Inner Mongolia Medical University from April 2015 to April 2016 were selected for analysis. These patients were divided into control group (n=58) and study group (n=58), according to the operation methods applied. The control group was treated by open chest lung cancer eradication, whereas the study group was treated by thoracoscopic radical resection of pul- monary carcinoma. The clinical index, incidence of complications and life quality score in the two groups were compared. Results There was no significant difference between the two groups of lymph nodes dissected (P 〉 0.05). The intraoperative amount of bleeding, drainage tube placement time, VAS score 24 hours after operation and the length of hospital stay in the study group were better than those in the control group, with highly statistically significant difference (P 〈 0.01). The total incidence of complications in the study group was lower than that in the control group, with highly statistically significant difference (P 〈 0.01). Among the life quality scores, the function, emotional status, physcial conditions and social/family status in the study group were higher than the control group, with highly statistically significant difference (P 〈 0.01). Conclusion For patients with early NSCLC, thoracoscopic radical resection of pulmonary carcinoma can effectively improve the clinical effects, with less postoperative complications, high safety and good prognosis. Therefore, it has clinical popularization and application value.
作者 靳智勇 任海燕 梁俊国 JIN Zhiyong REN Haiyan LIANG Junguo(Department of Thoracic Surgery, the Affiliated Hospital of Inner Mongolia Medical University, Inner Mongolia Autonomous Region, Hohhot 010050, China)
出处 《中国医药导报》 CAS 2017年第29期85-88,共4页 China Medical Herald
基金 内蒙古自治区自然科学基金资助项目(2017MS08109)
关键词 非小细胞肺癌 胸腔镜下肺癌根治术 并发症 预后 Non-small cell lung cancer Thoraco-scopic radical resection of pulmonary carcinoma Complications Prognosis
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