摘要
目的:探讨颈动脉粥样硬化与原发性高血压(essential hypertension,EH)并发缺血性脑卒中的相关性。方法:选取82例EH患者为EH组,根据是否合并缺血性脑卒中分为单纯EH组(n=40)与EH并发缺血性脑卒中组(n=42),选取血压正常者80例为对照组。超声检测EH组与正常组的颈动脉内-中膜厚度、粥样硬化斑块面积及斑块回声强度。结果:EH组颈动脉内-中膜厚度、粥样斑块面积、斑块回声强度均明显大于对照组(P<0.05);高血压越严重,斑块面积越大,颈动脉的狭窄程度越高(P<0.05);单纯EH组的颈动脉斑块大于EH合并缺血性脑卒中组,内-中膜厚度小于EH合并缺血性脑卒中组(P<0.05)。结论:EH患者的颈动脉粥样硬化程度高于血压正常者,且EH合并缺血性脑卒中患者的颈动脉硬化程度更高。
Objective:To explore the relationship between carotid atherosclerosis and essential hypertension (EH) complicated with ischemic cerebral stroke.Methods:A total of 82 EH patients were selected as EH group and divided into single EH group (n =40) and EH complicated with ischemic cerebral stroke group (n = 42) based on whether they were complicated with ischemic cerebral stroke.Another 80 people with normal blood pressure served as control group.Ultrasound was used to detect the carotid intima-media thickness,atherosclerotic plaque size and plaque echo intensity in EH group and normal group.Results:EH group was evidently higher than control group in carotid intima-media thickness,atherosclerotic plaque size and plaque echo intensity (P〈0.05).The severer the hypertension was,the larger the plaque size and the higher then stenosis of carotid artery became (P〈0.05).Single EH group was markedly higher in carotid atherosclerotic plaque and notably smaller in carotid intima-media thickness than EH complicated with ischemic cerebral stroke group (P〈0.05).Conclusion:Patients with EH are higher than those with normal blood pressure,but lower than those with EH complicated with ischemic cerebral stroke in carotid atherosclerotic severity.
出处
《川北医学院学报》
CAS
2017年第5期785-787,共3页
Journal of North Sichuan Medical College
关键词
原发性高血压
缺血性脑卒中
颈动脉粥样硬化
Essential hypertens ion
Ischemic cerebral stroke
Carotid atherosclerosis