摘要
目的探讨脑出血合并高钠血症患者经CRRT治疗的临床效果及预后。方法选取2014年3月~2015年5月我院收治的脑出血合并高钠血症患者57例,随机分为观察组29例与对照组28例。对照组患者接受内科常规治疗,而观察组患者则在此基础上接受连续性肾脏替代疗法(CRRT)治疗。治疗结束后,使用全自动生化仪对患者血清钠离子水平、尿素氮(BUN)以及肌酐(Scr)进行检测,并检测各项生命体征。结果观察组患者死亡率3.45%。对照组为死亡率28.57%,显著高于观察组(P<0.01)。接受CRRT治疗后,观察组患者血钠离子、BUN与Scr水平均较治疗前下降(P<0.05)。治疗后进行组间比较,观察组患者血钠离子、BUN与Scr水平均低于对照组患者(P<0.05)。心率和平均动脉压则与治疗前差异无统计学意义(P>0.05)。结论在内科常规治疗的基础上,对脑出血合并高钠血症患者进行CRRT治疗,能够有效纠正电解质紊乱,并且改善肾功能和患者预后,较为安全。
Objective To investigate the clinical effect and prognosis of cerebral hemorrhage complicated with hyponatremia after CRRT treatment. Methods 57 cases of cerebral hemorrhage complicated with hyponatremia from March 2014 to May 2015 in our hospital were enrolled in the study,and were divided into the observation group（29 cases） and the control group（28 cases） randomly.The patients in the control group received routine medical treatment,while the patients in the observation group received continuous renal replacement therapy （CRRT）.Serum sodium level,urea nitrogen （BUN） and creatinine （Scr） were detected,and the vital signs were detected after treatment. Results The mortality rate of observation group was 3.45%,and that of control group was 28.57%,which was significantly higher than that in the observation group （P 〈 0.01）.After CRRT treatment,the serum sodium ion,BUN and Scr levels of observation group were lower than those before treatment（P 〈 0.05）,and the serum sodium ion,BUN and Scr levels of observation group were lower than those of the control group（P 〈 0.05）.The heart rate and mean arterial pressure were no significantly different between before and after treatment （P〈0.05）. Conclusion On the basis of conventional medical treatment,CRRT treatment of cerebral hemorrhaze complicated with hvDonatremia can effectivelv correct the electrolvte disturbance.
出处
《中国医药科学》
2017年第19期221-223,共3页
China Medicine And Pharmacy
关键词
脑出血
高钠血症
连续性肾脏替代疗法
疗效
Cerebral hemorrhage
Hyponatremia
Continuous renal replacement therapy
Curative effect
