摘要
目的了解和掌握新疆维吾尔族和汉族健康人群幽门螺旋杆菌(HP)感染的流行病学资料,为HP的预防和治疗提供科学依据。方法选取2014年6月至2015年5月来我院健康体检人群2 188例为调查研究对象,采用14C-尿素呼气试验法(14C-UBT)检测HP感染率,采取自制研究问卷调查表,并就民族、性别、年龄、生活习惯、慢性病史等感染相关因素进行分析。结果受试人群总的HP感染率为43.88%(960/2 188),男性感染率为42.98%(618/1 438),女性感染率为45.60%(342/750),男女性别间差异无统计学意义(P>0.05)。维吾尔族HP感染率为65.61%(206/314),汉族为40.23%(754/1 874),维族、汉族HP感染率比较差异有统计学意义(P<0.05)。维族和汉族随着年龄的增长HP感染率呈现不同的趋势;在维族受试者中,31~40岁年龄段HP感染率最高,达71.76%(61/85);在汉族受试者中,51~60岁年龄段HP感染率最高,达46.29%(162/350)。吸烟及饮酒对维族、汉族HP的感染影响明显,组间差异有统计学意义(P<0.05);HP的感染与高血压、冠心病无明显相关性,差异无统计学意义(P>0.05)。结论维族、汉族总的HP感染率接近全国普通人群HP感染率底线;HP感染率与民族、性别、年龄、生活方式、饮食、慢性病史等因素有关。
Objective To investigate and understand the epidemiological data of Helicobacter pylori（HP）infection among Uygur and Han healthy population in Xinjiang,and provide scientific basis for prevention and treatment of HP infection.Methods From June 2014 to May 2015,2 188 healthy cases were collected in our hospital.14 C-urea breath test method（14 C-UBT）was used to detect HP infection. The relationship among infection and ethnic,gender,age,lifestyle,chronic disease history were analyzed by taken self-study questionnaire.Results The HP infection rate was 43.88%（960/2 188）.The male infection rate was 42.98%（618/1 438） and the female infection rate was 45.60%（342/750）;there was no significant difference between males and females infection rate（P〉0.05）. HP infection rate of Uyghur population was65.61%（206/314）,and that of Han population was 40.23%（754/1 874）. The difference of HP infection rate between Uyghur and Han people was statistically significant（P〈0.05）. The HP infection rate of Uyghur and Han people showed a different trend with age. The highest HP infection rate[71.76%（61/85）]of 31~40 years old in Uyghur population was the highest. In Han population,the HP infection rate of 51~60 years old was the highest,46.29%（162/350）.The infection of HP were significantly affected by smoking and drinking for Uyghur and Han people（P〈0.05）. There was no significant correlation associated with hypertension,coronary heart disease for HP infection（P〉0.05）. Conclusions The HP infection rate of Uyghur and Han people was similar to the infection rate of the general population. HP infection rate was related to ethnic,sex,age,lifestyle,diet,history of chronic disease,etc.
作者
阿依努尔.阿合曼
凯撒.尼亚孜
高峰
AYINUER A-he-man KAISA Ni-ya-zi GAO Feng(Department of Gastroenterology, Xinjiang Uygrur Autonomous Region Hospital, Urumqi, XinJiang 830001, China)
出处
《热带医学杂志》
CAS
2017年第10期1407-1410,1424,共5页
Journal of Tropical Medicine
基金
乌鲁木齐市科学技术计划项目(141310022)
