摘要
目的:探讨老年高血压病患者血浆B型钠尿肽(BNP)变化及其临床价值。方法:选取老年高血压病患者85例,同期住院的老年体检者35例为对照组,测定两组的血浆BNP和左室射血分数(EF)、左室舒张末内径(LVEDD)、左室缩短率(FS)、左房内径(LAD)。结果:老年高血压病患者BNP高于老年体检者,差异有统计学意义(P<0.05)。两组间LVEDD、FS差异有统计学意义(P<0.05),EF、LAD差异无统计学意义(P>0.05)。BNP与患者LVEDD、FS、LAD呈显著相关,差异有统计学意义(P<0.05)。结论:血浆BNP在老年高血压病患者中明显增高,其检测对于评价左心功能有着重要的临床价值。
Objective To explor the change of brain natriuertic peptide（ BNP） and its clinical value in elderly patients with hypertension. Method 85 elderly patients with hypertension were enrolled. Another 35 healthy subjects were chosen as control group. Sample the venous blood to test the BNP and examine the index of left ventricular ejection fraction（ LVEF）,left ventricular end diastolic diameter（ LVEDD）,left ventricular fraction shortening（ FS）,left atrial diameter（ LAD） by cardiac ultrasound. Results Compared the hypertension group and the control group,the difference in the BNP level was significant（ P〈0. 05）. The value of LVEDD was significantly higher than those in the control group（ P〈0. 05）,while its value of FS was significantly lower than that in the control group（ P〈0. 05）. There were no significant difference in the values of EF and LAD between the two groups（ P〉0. 05）. There was significant relationship between BNP and LVEDD、FS、LAD（ P〈0. 05）. Conclusion Plasma BNP levels are significantly elevated in elderly patients with hypertension,which is of great clinical value to be used in the evaluation of cardiac function.
出处
《吉林医学》
CAS
2017年第11期2024-2025,共2页
Jilin Medical Journal
关键词
高血压病
BNP
左心功能
Hypertension
Brain natriuertic peptide
Left cardiac function
