摘要
目的探讨盐酸罂粟碱对常规治疗无效的结石性肾绞痛患者疼痛的缓解作用。方法选择我院2015年5月~2017年5月收治的常规解痉镇痛治疗无效的结石性肾绞痛患者72例作为研究对象,根据用药方案不同分组,A组36例采用盐酸罂粟碱治疗,B组36例采用山莨菪碱与赖氨匹林静脉滴注,对两组患者治疗后疗效、疼痛变化、不良反应进行观察。结果 A组患者用药后总有效率为97.22%,与B组(83.33%)比较,差异有统计学意义(P<0.05);治疗前,两组患者疼痛视觉模拟评分(VAS)无明显差异(P>0.05),治疗1 h、2 h、3 h时,两组患者VAS评分明显低于治疗前,且A组均较B组低,差异有统计学意义(P<0.05)。A组用药后不良反应发生率为19.44%明显低于B组的41.67%,差异有统计学意义(P<0.05)。结论盐酸罂粟碱对常规治疗无效的结石性肾绞痛具有较高治疗价值,可快速缓解疼痛,且安全性高,值得临床推广应用。
Objective To probe into the alleviating effects of papaverine hydrochloride for degree of pain in patients with calculous colic with ineffective conventional treatment. Methods 72 cases of patients with calculous renal colic who ineffective with conventional antispasmodic analgesia and who accepted treatments in our hospital from May,2015 to May,2017 were selected as the research objects,and were grouped according to the different medication.The A group of 36 patients were treated with papaverine hydrochloride,while the B group of 36 cases were treated with Anisodamine and intravenous infusion of aspisol.Then,the clinical effect,pain changes and adverse reactions of two groups of pa-tients were observed after the treatment. Results The total effective rate in the A group of patients was 97.22%, com-pared with that B group of 83.33%,the difference was statistically significant （P〈0.05）.Before the treatment,there was no significant difference in pain visual analogue scale（VAS） between the two groups （P〉0.05）.When treated with 1h, 2h and 3h,the VAS scores of two groups of patients were significantly lower than those before the treatment,and the A group was lower than the B group, the difference was statistically significant（P〈0.05）. The rate of adverse reaction in Group A （19.44%）was obviously lower than that in Group B（41.67%）,the difference was statistically significant（P〈0.05）. Conclusion The papaverine hydrochloride for patients with calculous colic with ineffective conventional treatment which have high treatment value,and which can quickly relieve pain and the safety are high,thus it is worthy to be promoted and applied in the clinical.
作者
陈伟
梁雅灵
宋勤海
熊伟
CHEN Wei;LIANG Yaling;SONG Qinhai;XIONG Wei(Department of Emergency,the People＇s Hospital of teshan City in Sichuan Province,Leshan 614000,China;Department of Geriatrics,the People＇s Hospital of teshan City in Sichuan Province,teshan 614000,China)
出处
《中国现代医生》
2017年第30期93-95,共3页
China Modern Doctor
关键词
结石性
肾绞痛
盐酸罂粟碱
疼痛程度
Calculi
Renal colic
Papaverine hydrochloride
Pain degree
