摘要
目的比较分析甘精胰岛素与门冬胰岛素30在2型糖尿病治疗中的治疗效果。方法选择2型糖尿病患者80例,将其按照不同治疗方式分为对照组和观察组,每组40例。给予两组患者二甲双胍片作为基础降糖药物,在此基础上,对照组患者添加甘精胰岛素进行治疗,观察组则添加门冬胰岛素30进行治疗,将两组患者的治疗效果、不良反应发生率与治疗成本进行对比。结果经过治疗之后,对照组与观察组患者空腹血糖[对照组为(6.21±1.10)mmol/L,观察组为(6.18±1.07)mmol/L]、餐后2 h血糖[对照组为(7.85±1.21)mmol/L,观察组为(7.81±1.23)mmol/L]均显著下降,与治疗前[对照组为(10.43±1.23)mmol/L、(10.32±1.41)mmol/L,观察组为(14.25±2.13)mmol/L、(14.16±2.32)mmol/L]相比差异具有统计学意义(P<0.05),治疗后两组患者空腹血糖、餐后2 h血糖相差较小,差异无统计学意义;两组患者不良反应发生率(观察组为7.50%,对照组为12.50%)均较低,差异无统计学意义;观察组患者药物费用(885.74±11.53)元明显低于对照组(1 625.00±15.32)元,差异具有统计学意义(P<0.05)。结论甘精胰岛素与门冬胰岛素30在2型糖尿病患者中的治疗效果均较佳,能够显著降低糖尿病患者的空腹血糖和餐后2 h血糖;两种药物不良反应发生率均较低,安全性较高,但与甘精胰岛素相比,门冬胰岛素30治疗成本明显较低,在实际治疗中可根据患者实际情况选择合适药物。
Objective To compare the efficacy of insulin glargine and insulin aspart 30 in the treatment of type 2 diabetes mellitus. Methods A total of 2 patients with type 80 diabetes mellitus were selected and divided into control group and observation group according to different treatment methods, with 40 cases in each group. Two groups of patients were given metformin tablets as the basis of hypoglycemic drugs, on this basis, the patients in the control group with insulin glargine treatment, observation group added insulin aspart 30 treatment, the two groups of patients, the incidence of adverse reactions were compared with the cost of treatment. Results After treatment, the control group and the observation group were fasting blood glucose [the control group is(6.21 ± 1.10)mmol/L, the observation group was(6.18 ± 1.07)mmol/L], 2 h postprandial blood glucose [the control group is(7.85 ± 1.21)mmol/L, the observation group was(7.81 ± 1.23)mmol/L] decreased significantly, and before treatment [the control group is(10.43 ± 1.23)mmol/L,(10.32 ± 1.41)mmol/L, the observation group was(14.25 ± 2.13)mmol/L,(14.16 ± 2.32)mmol/L] with significant difference(P<0.05), the two groups after treatment in patients with fasting blood glucose, 2 h postprandial blood glucose were less, the difference was not statistically significant; the incidence of adverse reactions in the two groups(the observation group was 7.50%, the control group was 12.50%)were the lower, the difference was not statistically significant; the patients in the observation group were drug costs(885.74 ± 11.53) was significantly lower than the control group(1 625.00 ± 15.32), the difference was statistically significant(P<0.05). Conclusion Insulin glargine and insulin aspart 30 in patients with type 2 diabetes treatment had a better effect, can significantly reduce the diabetes fasting blood glucose and postprandial 2 h blood glucose; adverse drug reaction of the two low incidence, high safety, but with insulin glargine, insulin aspart 30 was significantly higher than the cost of treatment low, in the actual treatment can choose appropriate drugs according to the actual situation of patients.
出处
《当代医学》
2017年第34期23-25,共3页
Contemporary Medicine
关键词
甘精胰岛素
门冬胰岛素30
2型糖尿病
空腹血糖
餐后2
h血糖
Insulin glargine
Insulin aspart 30
Type 2 diabetes mellitus
Fasting blood glucose
Postprandial 2 h blood glucose
