摘要
目的探讨奥曲肽在急性胰腺炎患者中的临床疗效及对胰腺血流指标的影响.方法选取2015年10月至2016年7月期间本院收治的82例急性胰腺炎患者为研究对象,将82例患者按照随机分配的原则分为对照组41例和观察组41例,对照组进行常规急性胰腺炎治疗,观察组则在常规治疗的基础上加用奥曲肽,然后统计与比较2组的临床总有效率、治疗前后的胰头及胰尾血流指标.结果观察组中轻型及重型患者的临床总有效率均高于对照组(P<0.05),治疗后不同时间观察组的胰头及胰尾血流指标均明显好于对照组,差异有统计学意义(P<0.05).结论奥曲肽在急性胰腺炎患者中的临床疗效较好,且可显著地改善胰腺血流状态,认为奥曲肽在急性胰腺炎患者中应用价值较高.
Objective To study and observe the clinical effect of octreotide in the patients with acutepancreatitis and its influence on the pancreatic blood flow.Methods 82 patients with acute pancreatitis in ourhospital from October 2015 to July 2016 were set as the research object,and 82 patients were divided into controlgroup 41 cases and observation group 41 cases according to the principle of random allocation. Patients in the controlgroup were treated with routine treatment of acute pancreatitis,while patients in the observation group were treatedwith octreotide on the basic treatment,then the total clinical effective rates,pancreatic head and tail blood flowindexes before and after the treatment of two groups were analyzed and compared. Results The total clinicaleffective rates of observation group with mild and severe pancreatitis were higher than those of control group,thepancreatic head and tail blood flow indexes at different time after the treatment were all obviously higher than those ofcontrol group,all 〈0.05,the differences were all significant. Conclusion The clinical effect of octreotide on thepatients with acute pancreatitis is better,and it can significantly improve the pancreatic blood flow state,so itsapplication value in the patients with acute pancreatitis is higher.
出处
《昆明医科大学学报》
CAS
2017年第9期83-86,共4页
Journal of Kunming Medical University
基金
云南省应用基础研究基金资助项目(2015FB063)
关键词
奥曲肽
急性胰腺炎
临床疗效
胰腺血流指标
Octreotide
Acute pancreatitis
Clinical effect
Pancreatic blood flow indexes
