摘要
目的探讨短程团体认知行为治疗(short-range group cognitive behavioral therapy,SGCBT)、个体认知行为治疗(individual cognitive behavioral therapy,ICBT)联合药物治疗与单一抗抑郁药物治疗的临床疗效。方法将120例住院老年抑郁症患者按随机数字表法分成对照组、研究1组和研究2组各40例。3组采用统一药物艾司西酞普兰治疗,对照组仅使用抗抑郁药物,研究1组使用SGCBT联合艾司西酞普兰,研究2组采用ICBT联合艾司西酞普兰,共观察8周。各组均采用老年抑郁量表(GDS)及汉密尔顿抑郁量表(HAMD)进行疗效评价。结果研究1、2组与对照组的HAMD和GDS评分均显著下降(P<0.01);研究1组在第2周较研究2组的HAMD减分较低,第3~8周差异有统计学意义(P<0.01)。结论对老年住院抑郁症患者,认知行为治疗联合药物治疗方法较单纯的药物治疗效果更佳,其中SGCBT比ICBT起效更快,疗效更好,因此,对于住院老年抑郁症患者,SGCBT是值得推广的有效治疗方法。
Objective To explore the clinical effect of senile depression patients with short-range group cognitive behavioral therapy, individual cognitive behavioral therapy ,joint antidepressant drugs treatment and single antidepressant drug treatment. Methods One hundred and twenty inpatients were divided into control, study no. 1 and study no. 2 groups,40 in each group. The three groups received the uniform drug of escitalopram. The control group was given the antidepressants only. The study no. 1 group was treated with the combination of short-range group cognitive-behavioral therapy （SGCBT） and escitalopram while the study no. 2 group was treated with the combination of individual cognitive-behavioral therapy （ICBT） and escitalopram. The total observation course was 8 week. The geriatric depression scale （GDS） and the Hamilton depression rating scale （HAMD） were used to evaluate the treatment effectiveness. Results The scores of HAMD and GDS in the study no. 1 and no. 2 groups were significantly decreased when compared to the control group （ P 〈 0.01 ）. The HAMD reduction in the study no. 1 group was lower at the 2 nd week than that in the study no. 2 group （P 〈 0. 01） but there was no significant difference from the 3rd to 8th week. Conclusion For the hospitalized senile depression phtients, cognitive-behavioral therapy combined with drug therapy is better than the single drug treatment in which SGCBT is faster and more effective than ICBT. Therefore, the SGCBT is appealing to effective treatment for the hospitalized elderly patients with depression.
出处
《实用医院临床杂志》
2017年第6期90-93,共4页
Practical Journal of Clinical Medicine
基金
四川省科技支撑计划项目(编号:15ZC0224)
关键词
老年抑郁症
短程团体认知行为治疗
个体认知行为治疗
抗抑郁剂
对照研究
Senile depression
Short-range group cognitive：behavioral therapy
Individual cognitive-behavioral therapy
Antide- pressant drugs
Control study
