摘要
肝泡状棘球蚴病是人感染多房棘球蚴绦虫的虫卵所引起的一种严重的寄生虫病。研究肝泡状棘球蚴病的发生发展机制对于探索新的诊疗手段具有重要的意义,而建立良好的实验动物模型是进行深入研究的基础。通过查阅国内外包虫病动物模型建立的相关文献,对建立棘球蚴病实验动物模型的保种、实验动物的选择、建模方法、评估手段及其优缺点进行了综述,旨在为棘球蚴病动物模型相关研究提供参考。
Hepatic alveolar echinococcosis （HAE） is a serious parasitic disease caused by the infection with the eggs of Echinococcus multilocularis Leuckart. Research on the mechanism of the development and progression of HAE helps to explore new methods for its diagnosis and treatment, and the establishment of good animal models is the basis for further studies on HAE. With reference to the articles on the establishment of HAE animal models in China and foreign countries, this article reviews breed conservation, selection of experimental animals, and methods for model establishment, as well as evaluation methods and their own advantages and disadvantages, in order to provide a reference for studies on HAE animal models.
作者
周启锋
任利
张灵强
樊海宁
ZHOU Qifeng;REN Li;ZHANG Lingqiang;et al(Medical College of Qinghai University, Xining 810001, China)
出处
《临床肝胆病杂志》
CAS
2017年第11期2247-2250,共4页
Journal of Clinical Hepatology
基金
青海大学2014年度中青年科研基金项目(2014-QYT-1)
关键词
棘球蚴病
肝
模型
动物
综述
echinococcosis, hepatic
models, animal
review
