摘要
生物材料研究领域的前沿是可吸收材料,因为可吸收材料植入生物体内以后,能够在生物体内发生反应,并被吸收或排出体外。目前,在骨科相关领域植入的生物材料中,应用较多的可吸收生物材料是PLA(聚乳酸)和PGA(聚羟基乙酸),但这些高分子聚合材料具有降解产物呈酸性、容易引发炎症、力学性能较弱、负载能力较差等缺点。镁合金材料有非常好的力学物理性能,且对人体无毒,并能在体内经过腐蚀而逐步被降解,其作为一种有发展潜力的可吸收植入生物材料,很可能成为新一代颅颌面骨骼的内固定材料。本文就镁基合金作为可吸收植入材料的优点、研究现况及未来研究方向作一综述。
Biodegradable biomaterials can be decomposed in vivo and the decomposed products can be absorbed or excreted by the organism. Widely used in bone implantation,the biodegradable materials are mainly polymers such as polylactic acid（ PLA）,polyglycolic acid（ PGA）,but the strength of these materials are generally low,it is difficult to bear large load,and the acidic degradation products,may lead to inflammation. Magnesium and its alloy not only has good mechanical properties,and non-toxic to humans,the corrosion can be gradually degraded in vivo,as a kind of promising biodegradable implant biomaterials magnesium is becoming increasingly popular and very likely to be a new generation of craniofacial fixation material. In this paper,the present research status of Mg based alloys is reviewed,and the advantages of Mg based alloys are proposed.
出处
《牙体牙髓牙周病学杂志》
CAS
2017年第11期669-672,共4页
Chinese Journal of Conservative Dentistry
基金
军事口腔医学国家重点实验室开放课题项目
关键词
可吸收
镁基合金
生物
材料
absorbable magnesium based alloy biomaterials
