摘要
质子泵抑制剂(PPI)是治疗胃酸异常分泌和酸相关性疾病的一线药物,对消化性溃疡、幽门螺杆菌(Hp)感染、上消化道出血、胃食管反流病(GERD)等疾病疗效显著。近期研究表明PPI可应用于其他临床领域,如肿瘤、肺纤维化、房颤、结核菌感染、早产等,为这些疾病的治疗提供了新思路。本文就PPI的临床应用新领域作一综述。
Proton pump inhibitor （PPI） is the firstline drug for treatment of abnormal secretion of gastric acid and acid related diseases, and is effective in the treatment of peptic ulcer, Helicobacter pylori （Hp） infection, upper gastrointestinal bleeding and gastroesophageal reflux disease （GERD）. Recent studies have shown that PPI could be used in other clinical fields, such as tumor, pulmonary fibrosis, atrial fibrillation, tuberculosis infection and premature delivery, which provides new insights for the treatment of these diseases. This article reviewed the new fields of clinical application of PPI.
出处
《胃肠病学》
2017年第11期696-699,共4页
Chinese Journal of Gastroenterology
基金
国家自然科学基金项目(81470808)
关键词
质子泵抑制剂
肿瘤
肺纤维化
心房颤动
早产
治疗
Proton Pump Inhibitors
Neoplasms
Pulmonary Fibrosis
Atrial Fibrillation
Premature Birth
Therapy
